Correlation Engine 2.0
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QuickView for CBS (gene)

Gene Symbol:
CBS Homo sapiens Homo sapiens
Full name:
HIP4, cystathionine beta-synthase, beta-thionase, methylcysteine synthase, serine sulfhydrase
Genomic Location:
Chr 21: 43346370-43369490
The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency ...
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Gallus gallus Bos taurus Danio rerio Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 21

GO Molecular Function

carbon monoxide binding | cysteine synthase activity | cofactor binding | modified amino acid binding | cation binding | neurotransmitter binding | enzyme binding | vitamin binding | transferase activity, transferring alkyl or aryl (other than methyl) groups | coenzyme binding | nitrite reductase (NO-forming) activity | hydro-lyase activity | lyase activity | pyridoxal phosphate binding | catalytic activity | ubiquitin-like protein ligase binding | anion binding | nitrite reductase activity | identical protein binding | cystathionine beta-synthase activity | ion binding | organic cyclic compound binding | vitamin B6 binding | S-adenosyl-L-methionine binding | tetrapyrrole binding | oxygen binding | protein binding | protein homodimerization activity | ubiquitin protein ligase binding | protein dimerization activity | oxidoreductase activity, acting on other nitrogenous compounds as donors | transferase activity | nitric oxide binding | heme binding | drug binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | small molecule binding

GO Biological Process

response to extracellular stimulus | cysteine synthase activity | sulfur compound metabolic process | cellular response to extracellular stimulus | cellular amino acid catabolic process | cellular process | organic substance catabolic process | toxin metabolic process | serine family amino acid metabolic process | cysteine biosynthetic process | sulfur amino acid biosynthetic process | cellular amino acid metabolic process | catabolic process | L-cysteine catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | nitrite reductase (NO-forming) activity | carboxylic acid catabolic process | response to stress | cellular amino acid biosynthetic process | cellular nitrogen compound metabolic process | cellular biosynthetic process | serine family amino acid biosynthetic process | L-serine metabolic process | sulfur amino acid metabolic process | nitrogen compound metabolic process | cysteine biosynthetic process via cystathionine | cellular response to stress | small molecule metabolic process | nitrite reductase activity | biosynthetic process | cell communication | transsulfuration | drug metabolic process | carboxylic acid metabolic process | cysteine biosynthetic process from serine | DNA metabolic process | metabolic process | oxidation-reduction process | oxidoreductase activity, acting on other nitrogenous compounds as donors | nucleobase-containing compound metabolic process | L-cysteine metabolic process | organic substance metabolic process | homoserine metabolic process | DNA protection | hydrogen sulfide biosynthetic process | organonitrogen compound catabolic process | homocysteine metabolic process | organic acid metabolic process | sulfur amino acid catabolic process | cysteine metabolic process | homocysteine catabolic process | sulfur compound catabolic process | toxin biosynthetic process | heterocycle metabolic process | serine family amino acid catabolic process | L-serine catabolic process | cellular metabolic process | hydrogen sulfide metabolic process | oxidoreductase activity | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular