QuickView for CCAR2;jsessionid=9A4BA2D0F61958988DF3A757141A5209 (gene)
- Gene Symbol:
- CCAR2
Homo sapiens - Full name:
- cell cycle and apoptosis regulator 2
- Synonyms:
- DBC-1, DBC1, KIAA1967, NET35, p30 DBC, p30DBC, cell cycle and apoptosis regulator protein 2, cell division cycle and apoptosis regulator protein 2, deleted in breast cancer 1, p30 DBC protein
- Genomic Location:
- Chr 8: 22518202-22533929
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
8p21.3
GO Molecular Function
RNA polymerase II complex binding | RNA polymerase binding | enzyme binding | nucleic acid binding | enzyme inhibitor activity | molecular function regulator | RNA polymerase core enzyme binding | organic cyclic compound binding | transcription coactivator activity | protein binding | nuclear receptor transcription coactivator activity | enzyme regulator activity | transcription coregulator activity | basal RNA polymerase II transcription machinery binding | heterocyclic compound binding | RNA binding
GO Biological Process
RNA metabolic process | response to radiation | positive regulation of macromolecule biosynthetic process | RNA processing | positive regulation of apoptotic process | regulation of programmed cell death | negative regulation of cellular process | negative regulation of RNA biosynthetic process | negative regulation of proteolysis | positive regulation of cellular biosynthetic process | cellular process | mitochondrial fragmentation involved in apoptotic process | negative regulation of ubiquitin-dependent protein catabolic process | negative regulation of signaling | negative regulation of nucleic acid-templated transcription | negative regulation of apoptotic process | regulation of proteolysis | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | regulation of canonical Wnt signaling pathway | negative regulation of cellular metabolic process | negative regulation of apoptotic signaling pathway | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | positive regulation of response to DNA damage stimulus | positive regulation of DNA damage checkpoint | negative regulation of cellular protein catabolic process | response to UV | response to stimulus | enzyme inhibitor activity | RNA splicing | regulation of cellular response to heat | regulation of cellular protein catabolic process | response to stress | cellular nitrogen compound biosynthetic process | programmed cell death | rhythmic process | cellular nitrogen compound metabolic process | apoptotic mitochondrial changes | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | mRNA metabolic process | cellular biosynthetic process | mitochondrion organization | cell-cell signaling | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage | molecular function regulator | cell surface receptor signaling pathway involved in cell-cell signaling | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | apoptotic process | response to light stimulus | nitrogen compound metabolic process | regulation of signal transduction | Wnt signaling pathway | negative regulation of growth | regulation of protein stability | negative regulation of catalytic activity | cellular response to DNA damage stimulus | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | regulation of catalytic activity | regulation of intrinsic apoptotic signaling pathway | regulation of gene expression | cellular response to stress | cell cycle | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of DNA damage checkpoint | biosynthetic process | positive regulation of cell cycle checkpoint | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | regulation of apoptotic signaling pathway | cell communication | regulation of cellular metabolic process | regulation of protein deacetylation | regulation of protein metabolic process | positive regulation of signal transduction | transcription coactivator activity | regulation of RNA metabolic process | negative regulation of cell growth | regulation of proteasomal ubiquitin-dependent protein catabolic process | regulation of growth | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | cell surface receptor signaling pathway | metabolic process | regulation of protein catabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nuclear receptor transcription coactivator activity | negative regulation of programmed cell death | regulation of proteasomal protein catabolic process | positive regulation of cell death | regulation of response to DNA damage stimulus | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of intrinsic apoptotic signaling pathway | regulation of intrinsic apoptotic signaling pathway in response to DNA damage | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | negative regulation of cellular protein metabolic process | gene expression | positive regulation of programmed cell death | regulation of Wnt signaling pathway | regulation of DNA-templated transcription, elongation | transcription, DNA-templated | positive regulation of canonical Wnt signaling pathway | negative regulation of protein catabolic process | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | enzyme regulator activity | cellular macromolecule biosynthetic process | regulation of circadian rhythm | organelle organization | regulation of cell growth | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | heterocycle metabolic process | positive regulation of metabolic process | positive regulation of Wnt signaling pathway | cellular metabolic process | mRNA processing | regulation of cell death | negative regulation of cell death | regulation of ubiquitin-dependent protein catabolic process | negative regulation of proteolysis involved in cellular protein catabolic process | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | negative regulation of proteasomal protein catabolic process
GO Cellular Component
mitochondrial matrix | DBIRD complex | chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | chromatin | nuclear chromosome | ribonucleoprotein complex | spliceosomal complex | mitochondrion | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | intracellular
