QuickView for CCL18 (gene)

Gene Symbol:

CCL18 Homo sapiens

Full name:

C-C motif chemokine ligand 18

Synonyms:

AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18, C-C motif chemokine 18, CC chemokine PARC, CC chemokine ligand 18, alternative macrophage activation-associated CC chemokine 1, chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated), chemokine (C-C), dendritic, dendritic cell chemokine 1, macrophage inflammatory protein 4, pulmonary and activation-regulated chemokine, small inducible cytokine A18, small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary and activation-regulated

Genomic Location:

Chr 17: 31415756-31422954

Description:

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for...

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This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses.

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Orthologs:

Macaca mulatta ,  Pan troglodytes

External Links:

Entrez Gene

Cytogenetic Map:

17q12

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