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QuickView for CCNA2;jsessionid=22F855C2BFDD7F9C4867264A606F1DEF (gene)


Gene Symbol:
CCNA2 Homo sapiens Homo sapiens
Full name:
cyclin A2
Synonyms:
CCN1, CCNA, cyclin-A2, cyclin-A
Genomic Location:
Chr 4: 122957975-122964342
Description:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members function as regulators of the cell cycle. This protein binds and activates cyclin-dependent kinase 2 and thus promotes transition through G1/S and G2/M.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 4
4q27


Transcripts Names
NM_001237
Protein Names
Q6LER8
P20248
Q2M3U6
A8K7B6
Q4W5P4



GO Molecular Function

kinase binding | protein kinase regulator activity | kinase regulator activity | protein kinase binding | enzyme binding | cyclin-dependent protein kinase activity | molecular function regulator | catalytic activity | protein domain specific binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | enzyme regulator activity | kinase activity | cyclin-dependent protein serine/threonine kinase regulator activity

GO Biological Process

protein modification by small protein removal | cellular response to luteinizing hormone stimulus | regulation of cell cycle process | cellular response to decreased oxygen levels | positive regulation of macromolecule biosynthetic process | intracellular signal transduction | cellular response to platelet-derived growth factor stimulus | proteolysis | protein kinase regulator activity | response to luteinizing hormone | response to hormone | histone modification | positive regulation of fibroblast proliferation | response to drug | regulation of organelle organization | positive regulation of cellular biosynthetic process | cellular process | chromatin organization | cellular response to nitric oxide | kinase regulator activity | response to estradiol | regulation of mitotic nuclear division | response to hypoxia | regulation of cell cycle | response to growth factor | positive regulation of nitrogen compound metabolic process | response to inorganic substance | response to peptide hormone | interspecies interaction between organisms | regeneration | regulation of cellular process | cellular response to lipid | regulation of metabolic process | small GTPase mediated signal transduction | cellular response to organonitrogen compound | cellular component organization | protein deubiquitination | response to stimulus | cyclin-dependent protein kinase activity | response to cocaine | cellular response to xenobiotic stimulus | cellular response to hypoxia | response to stress | regulation of cell proliferation | response to peptide | cellular response to inorganic substance | cell cycle G1/S phase transition | cellular response to organic cyclic compound | positive regulation of RNA biosynthetic process | protein modification process | macromolecule modification | molecular function regulator | regulation of nucleic acid-templated transcription | response to nitrogen compound | cellular response to hormone stimulus | system development | regulation of cyclin-dependent protein serine/threonine kinase activity | response to oxygen levels | nitrogen compound metabolic process | multicellular organism development | cellular response to peptide hormone stimulus | phosphorus metabolic process | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | cellular response to oxidative stress | regulation of phosphorylation | cellular response to ammonium ion | positive regulation of cell cycle | regulation of gene expression | cellular response to stress | response to lipid | cellular response to peptide | cell cycle | cellular response to gonadotropin stimulus | positive regulation of cellular metabolic process | response to ammonium ion | cellular response to oxygen levels | regulation of nitrogen compound metabolic process | cellular response to alkaloid | response to oxidative stress | response to platelet-derived growth factor | cell division | regulation of cellular protein metabolic process | G2/M transition of mitotic cell cycle | phosphorylation | response to xenobiotic stimulus | mitotic cell cycle phase transition | protein phosphorylation | phosphate-containing compound metabolic process | sensory organ development | cellular response to drug | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | inner ear development | cell cycle G2/M phase transition | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of RNA metabolic process | histone phosphorylation | viral process | regulation of mitotic cell cycle | response to glucagon | protein metabolic process | regulation of fibroblast proliferation | cellular response to insulin-like growth factor stimulus | response to organic substance | regulation of kinase activity | cellular response to reactive nitrogen species | response to leptin | anatomical structure development | mitotic cell cycle | metabolic process | regulation of RNA biosynthetic process | ear development | protein kinase activity | cellular response to reactive oxygen species | organic substance metabolic process | animal organ development | response to reactive oxygen species | protein modification by small protein conjugation or removal | regulation of phosphate metabolic process | response to alkaloid | response to gonadotropin | cellular response to cocaine | cellular response to estradiol stimulus | signaling | covalent chromatin modification | regulation of transcription, DNA-templated | response to organic cyclic compound | cellular protein metabolic process | enzyme regulator activity | kinase activity | developmental process | organelle organization | cellular protein modification process | positive regulation of transcription, DNA-templated | Ras protein signal transduction | positive regulation of nucleic acid-templated transcription | cochlea development | response to organonitrogen compound | cell cycle phase transition | response to anesthetic | positive regulation of metabolic process | chromosome organization | cellular metabolic process | cellular response to organic substance | response to nitric oxide | regulation of cellular component organization | signal transduction | cellular response to leptin stimulus | animal organ regeneration | positive regulation of gene expression | cellular response to growth factor stimulus | cyclin-dependent protein serine/threonine kinase regulator activity | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | catalytic complex | protein kinase complex | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | pronucleus | nucleoplasm | transferase complex | cyclin A2-CDK2 complex | serine/threonine protein kinase complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | female pronucleus | cyclin-dependent protein kinase holoenzyme complex | cytosol | male pronucleus | intracellular