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QuickView for CCNK;jsessionid=16E7C2060EC546695E6EDC23B1B32379 (gene)


Gene Symbol:
CCNK Homo sapiens Homo sapiens
Full name:
cyclin K
Synonyms:
CPR4, cyclin-K
Genomic Location:
Chr 14: 99017492-99047605
Description:
The protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK a...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Schizosaccharomyces pombe Gallus gallus Pan troglodytes Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 14
14q32.2





GO Molecular Function

kinase binding | protein kinase regulator activity | kinase regulator activity | protein kinase binding | enzyme binding | cyclin-dependent protein kinase activity | protein serine/threonine kinase activity | RNA polymerase II CTD heptapeptide repeat kinase activity | molecular function regulator | catalytic activity | protein binding | cyclin-dependent protein serine/threonine kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | enzyme regulator activity | kinase activity | cyclin-dependent protein serine/threonine kinase regulator activity

GO Biological Process

positive regulation of cyclin-dependent protein serine/threonine kinase activity | RNA metabolic process | transcription by RNA polymerase II | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | snRNA metabolic process | protein kinase regulator activity | negative regulation of cellular process | positive regulation of phosphate metabolic process | interaction with symbiont | positive regulation of cellular biosynthetic process | cellular process | kinase regulator activity | negative regulation of viral life cycle | positive regulation of protein kinase activity | regulation of phosphorylation of RNA polymerase II C-terminal domain | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | snRNA transcription | negative regulation of cell cycle arrest | interspecies interaction between organisms | regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues | regulation of cellular process | regulation of metabolic process | positive regulation of cyclin-dependent protein kinase activity | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | response to stimulus | cyclin-dependent protein kinase activity | modulation by virus of host process | positive regulation of protein metabolic process | response to stress | cellular nitrogen compound biosynthetic process | snRNA transcription by RNA polymerase II | protein serine/threonine kinase activity | cellular nitrogen compound metabolic process | negative regulation of viral genome replication | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | protein modification process | RNA polymerase II CTD heptapeptide repeat kinase activity | cellular biosynthetic process | macromolecule modification | molecular function regulator | regulation of nucleic acid-templated transcription | regulation of cyclin-dependent protein serine/threonine kinase activity | nitrogen compound metabolic process | phosphorus metabolic process | cellular response to DNA damage stimulus | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | ncRNA transcription | positive regulation of cell cycle | modulation by host of viral process | regulation of gene expression | cellular response to stress | cell cycle | modification of morphology or physiology of other organism | regulation of cell cycle arrest | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | positive regulation of phosphorylation of RNA polymerase II C-terminal domain | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | negative regulation of viral process | biosynthetic process | cell division | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | phosphorylation | negative regulation by host of viral process | transcription elongation from RNA polymerase II promoter | protein phosphorylation | phosphate-containing compound metabolic process | positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of RNA metabolic process | viral process | regulation of viral process | positive regulation of molecular function | protein metabolic process | positive regulation of protein modification process | regulation of kinase activity | cyclin-dependent protein serine/threonine kinase activity | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | protein kinase activity | organic substance metabolic process | gene expression | positive regulation of kinase activity | negative regulation by host of viral genome replication | regulation of phosphate metabolic process | transcription, DNA-templated | negative regulation of cell cycle | regulation of transcription, DNA-templated | positive regulation of phosphorylation | cellular protein metabolic process | enzyme regulator activity | cellular macromolecule biosynthetic process | kinase activity | cellular protein modification process | positive regulation of transcription, DNA-templated | modulation by virus of host morphology or physiology | ncRNA metabolic process | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | regulation of viral genome replication | negative regulation of cell cycle process | regulation of viral life cycle | positive regulation of gene expression | cyclin-dependent protein serine/threonine kinase regulator activity | macromolecule metabolic process | DNA-templated transcription, elongation | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | catalytic complex | protein kinase complex | cell | nuclear lumen | intracellular organelle | protein-containing complex | nucleoplasm | transferase complex | cyclin K-CDK12 complex | serine/threonine protein kinase complex | membrane-bounded organelle | nucleus | organelle | cyclin K-CDK13 complex | membrane-enclosed lumen | cyclin-dependent protein kinase holoenzyme complex | intracellular