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QuickView for CCT8;jsessionid=05EA5B7CB76AE227735586E187A520F1 (gene)


Gene Symbol:
CCT8 Homo sapiens Homo sapiens
Full name:
chaperonin containing TCP1 subunit 8
Synonyms:
C21orf112, Cctq, D21S246, PRED71, T-complex protein 1 subunit theta, CCT-theta, TCP-1-theta, chaperonin containing TCP1, subunit 8 (theta), renal carcinoma antigen NY-REN-15
Genomic Location:
Chr 21: 29350518-29367881
Description:
This gene encodes the theta subunit of the CCT chaperonin, which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins. Alternative splicing results in multiple transcript variants of this gene. A pseudogene related to this gene is located on chromosome 1.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Bos taurus Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 21
21q21.3





GO Molecular Function

cadherin binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | ion binding | organic cyclic compound binding | cell adhesion molecule binding | purine ribonucleoside triphosphate binding | protein binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

regulation of telomere maintenance via telomerase | positive regulation of macromolecule biosynthetic process | exocytosis | positive regulation of cellular component organization | neutrophil activation | regulation of cellular localization | protein stabilization | regulation of localization | establishment of localization | regulation of organelle organization | positive regulation of cellular biosynthetic process | cellular process | secretion | leukocyte degranulation | localization | regulation of telomerase RNA localization to Cajal body | positive regulation of nitrogen compound metabolic process | cell recognition | regulation of cellular process | leukocyte activation | regulation of metabolic process | positive regulation of establishment of protein localization to telomere | cellular component organization | response to stimulus | regulation of cellular protein localization | neutrophil degranulation | leukocyte activation involved in immune response | positive regulation of cellular protein localization | toxin transport | sperm-egg recognition | reproduction | secretion by cell | cellular component assembly | positive regulation of telomere maintenance via telomere lengthening | reproductive process | positive regulation of organelle organization | regulation of protein stability | regulation of telomere maintenance | binding of sperm to zona pellucida | leukocyte mediated immunity | positive regulation of chromosome organization | positive regulation of cellular metabolic process | cell-cell recognition | regulation of protein localization to nucleus | regulation of nitrogen compound metabolic process | vesicle-mediated transport | positive regulation of protein localization to nucleus | fertilization | regulated exocytosis | positive regulation of telomere maintenance via telomerase | pore complex assembly | regulation of telomere maintenance via telomere lengthening | regulation of cellular metabolic process | positive regulation of DNA biosynthetic process | cell activation involved in immune response | myeloid cell activation involved in immune response | neutrophil activation involved in immune response | positive regulation of establishment of protein localization | single fertilization | positive regulation of protein localization to Cajal body | protein-containing complex assembly | regulation of establishment of protein localization | positive regulation of telomerase RNA localization to Cajal body | immune response | protein folding | regulation of chromosome organization | cell activation | positive regulation of protein localization to chromosome, telomeric region | positive regulation of telomere maintenance | positive regulation of DNA metabolic process | regulation of DNA biosynthetic process | neutrophil mediated immunity | positive regulation of metabolic process | immune system process | regulation of protein localization | sexual reproduction | regulation of cellular component organization | regulation of establishment of protein localization to chromosome

GO Cellular Component

secretory granule | azurophil granule lumen | supramolecular fiber | intracellular membrane-bounded organelle | microtubule organizing center | cytoplasmic vesicle | cell body | cell | nuclear lumen | vacuolar lumen | cytoplasmic vesicle lumen | microtubule | cytoplasm | intracellular organelle | ficolin-1-rich granule lumen | intermediate filament cytoskeleton | centrosome | protein-containing complex | cell projection | secretory vesicle | endomembrane system | zona pellucida receptor complex | nucleoplasm | cilium | vacuole | vesicle | chaperonin-containing T-complex | extracellular exosome | microtubule cytoskeleton | lytic vacuole | extracellular region | membrane-bounded organelle | extracellular vesicle | chaperone complex | nucleus | organelle | lysosome | extracellular space | membrane-enclosed lumen | azurophil granule | secretory granule lumen | cytosol | intracellular vesicle | cytoskeleton | intracellular | supramolecular complex | vesicle lumen