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QuickView for CCl4 (gene)


Gene Symbol:
CCL4 Homo sapiens Homo sapiens
Full name:
C-C motif chemokine ligand 4
Synonyms:
ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4, C-C motif chemokine 4, G-26 T-lymphocyte-secreted protein, MIP-1-beta(1-69), PAT 744, SIS-gamma, T-cell activation protein 2, chemokine (C-C motif) ligand 4, lymphocyte activation gene 1 protein, macrophage inflammatory protein 1-beta, secreted protein G-26, small inducible cytokine A4 (homologous to mouse Mip-1b)
Genomic Location:
Chr 17: 31455333-31457127
Description:
The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Bos taurus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 17
17q12


Transcripts Names
NM_002984
Protein Names
P13236



GO Molecular Function

chemokine activity | CCR chemokine receptor binding | signaling receptor binding | cytokine receptor binding | molecular function regulator | identical protein binding | chemokine receptor binding | protein binding | receptor regulator activity | CCR1 chemokine receptor binding | G-protein coupled receptor binding | receptor ligand activity | cytokine activity | CCR5 chemokine receptor binding

GO Biological Process

regulation of leukocyte chemotaxis | regulation of ERK1 and ERK2 cascade | positive regulation of locomotion | response to virus | response to cytokine | response to interleukin-1 | cell motility | regulation of localization | regulation of immune system process | cellular response to tumor necrosis factor | chemokine-mediated signaling pathway | defense response | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | interaction with symbiont | positive regulation of GTPase activity | cellular process | eosinophil chemotaxis | regulation of cell motility | localization | regulation of calcium-mediated signaling | chemokine activity | regulation of chemotaxis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | granulocyte chemotaxis | interspecies interaction between organisms | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular response to interferon-gamma | response to stimulus | positive regulation of natural killer cell chemotaxis | neutrophil chemotaxis | positive regulation of immune system process | positive regulation of protein metabolic process | response to stress | lymphocyte chemotaxis | G-protein coupled receptor signaling pathway | monocyte chemotaxis | cell-cell signaling | cell chemotaxis | molecular function regulator | leukocyte migration | locomotion | response to external biotic stimulus | regulation of signal transduction | cell migration | regulation of MAPK cascade | regulation of catalytic activity | regulation of phosphorylation | positive regulation of lymphocyte migration | positive regulation of chemotaxis | modification of morphology or physiology of other organism | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | lymphocyte migration | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | regulation of cellular component movement | positive regulation of hydrolase activity | positive regulation of calcium-mediated signaling | negative regulation of viral process | positive regulation of cell migration | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | response to toxic substance | regulation of GTPase activity | establishment or maintenance of cell polarity | regulation of leukocyte migration | negative regulation by host of viral transcription | cell communication | regulation of cellular metabolic process | positive regulation of leukocyte chemotaxis | inflammatory response | regulation of protein metabolic process | positive regulation of signal transduction | leukocyte chemotaxis | regulation of protein phosphorylation | regulation of locomotion | regulation of RNA metabolic process | positive regulation of transport | regulation of viral process | positive regulation of molecular function | regulation of signaling receptor activity | receptor regulator activity | positive regulation of protein modification process | response to organic substance | eosinophil migration | regulation of intracellular signal transduction | cell surface receptor signaling pathway | regulation of RNA biosynthetic process | cell adhesion | receptor ligand activity | immune response | cytokine activity | positive regulation of ion transport | positive regulation of leukocyte migration | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | response to interferon-gamma | positive regulation of MAPK cascade | regulation of lymphocyte chemotaxis | modulation by host of viral transcription | regulation of cell communication | signaling | positive regulation of phosphorylation | response to biotic stimulus | regulation of ion transport | cellular response to interleukin-1 | regulation of calcium ion transport | regulation of transport | innate immune response | regulation of viral transcription | positive regulation of metabolic process | immune system process | response to tumor necrosis factor | cellular response to organic substance | positive regulation of cell motility | neutrophil migration | chemotaxis | negative regulation of viral transcription | regulation of lymphocyte migration | positive regulation of calcium ion transport | response to other organism | positive regulation of signaling | signal transduction | mononuclear cell migration | regulation of signaling | regulation of phosphorus metabolic process

GO Cellular Component

extracellular region | extracellular space