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QuickView for CD147 (gene)


Gene Symbol:
BSG Homo sapiens Homo sapiens
Full name:
basigin (Ok blood group)
Synonyms:
5F7, CD147, EMMPRIN, OK, TCSF, basigin, OK blood group antigen, collagenase stimulatory factor, extracellular matrix metalloproteinase inducer, leukocyte activation antigen M6, tumor cell-derived collagenase stimulatory factor
Genomic Location:
Chr 19: 522325-534493
Description:
The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 19
19p13.3





GO Molecular Function

organic anion transmembrane transporter activity | anion transmembrane transporter activity | cadherin binding | cell-cell adhesion mediator activity | transmembrane transporter activity | organic acid transmembrane transporter activity | monosaccharide binding | transporter activity | ion transmembrane transporter activity | mannose binding | carboxylic acid transmembrane transporter activity | cell adhesion molecule binding | carbohydrate binding | protein binding | monocarboxylic acid transmembrane transporter activity | cell adhesion mediator activity | small molecule binding

GO Biological Process

cell morphogenesis | extracellular structure organization | cell motility | neuron projection morphogenesis | developmental process involved in reproduction | protein localization to cell periphery | organic anion transmembrane transporter activity | establishment of localization | response to hormone | anion transmembrane transporter activity | response to metal ion | cell differentiation | maternal placenta development | nervous system development | cell part morphogenesis | neurogenesis | generation of neurons | response to organophosphorus | cellular process | monocarboxylic acid transport | localization | cell projection morphogenesis | odontogenesis | neuron development | reproductive system development | female pregnancy | anion transport | multicellular organismal reproductive process | macromolecule localization | axon guidance | response to inorganic substance | response to peptide hormone | tissue development | cell recognition | regulation of cellular process | cell-cell adhesion mediator activity | transmembrane transporter activity | cellular component organization | response to stimulus | cell morphogenesis involved in neuron differentiation | monocarboxylic acid metabolic process | neuron projection guidance | response to peptide | organic acid transmembrane transporter activity | reproduction | cellular localization | dendrite self-avoidance | extracellular matrix organization | carboxylic acid transmembrane transport | leukocyte migration | locomotion | response to nitrogen compound | system development | reproductive process | multicellular organism development | cell migration | response to purine-containing compound | ion transmembrane transport | protein localization to plasma membrane | protein localization to membrane | axon development | organic substance transport | neuron recognition | animal organ morphogenesis | response to mercury ion | small molecule metabolic process | organic acid transport | ion transmembrane transporter activity | axonogenesis | pyruvate metabolic process | organic anion transport | cell morphogenesis involved in differentiation | cell communication | carboxylic acid transmembrane transporter activity | odontogenesis of dentin-containing tooth | decidualization | carboxylic acid metabolic process | neuron differentiation | multicellular organism reproduction | maternal process involved in female pregnancy | response to organic substance | anion transmembrane transport | anatomical structure development | organic acid transmembrane transport | cell surface receptor signaling pathway | cell projection organization | metabolic process | cellular protein localization | cell adhesion | neuron projection development | organic substance metabolic process | monocarboxylic acid transmembrane transporter activity | animal organ development | cell-cell adhesion | response to cAMP | cell adhesion mediator activity | transmembrane transport | signaling | response to organic cyclic compound | cell development | protein localization | organic acid metabolic process | carboxylic acid transport | anatomical structure morphogenesis | cellular macromolecule localization | reproductive structure development | developmental process | response to organonitrogen compound | embryo implantation | cell-cell adhesion via plasma-membrane adhesion molecules | ion transport | immune system process | cellular metabolic process | placenta development | chemotaxis | extracellular matrix disassembly | signal transduction | homophilic cell adhesion via plasma membrane adhesion molecules | multicellular organismal process

GO Cellular Component

secretory granule | integral component of membrane | intracellular membrane-bounded organelle | sarcolemma | neuron projection | adherens junction | organelle membrane | focal adhesion | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | cell-substrate junction | acrosomal vesicle | intracellular organelle | membrane microdomain | secretory granule membrane | melanosome | Golgi apparatus | cell projection | secretory vesicle | endomembrane system | plasma membrane | membrane raft | vesicle | extracellular exosome | mitochondrion | acrosomal membrane | integral component of plasma membrane | Golgi membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | vesicle membrane | extracellular space | cell periphery | axon | cell-substrate adherens junction | intracellular vesicle | intracellular | cell junction | membrane | cytoplasmic vesicle membrane | intrinsic component of plasma membrane