QuickView for CD200R1 (gene)

Gene Symbol:

CD200R1 Homo sapiens

Full name:

CD200 receptor 1

Synonyms:

CD200R, HCRTR2, MOX2R, OX2R, cell surface glycoprotein CD200 receptor 1, CD200 cell surface glycoprotein receptor, MOX2 receptor, cell surface glycoprotein OX2 receptor 1, cell surface glycoprotein receptor CD200

Genomic Location:

Chr 3: 114124222-114176627

Description:

This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a re...

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This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  IRF1_01 ,  STAT4_01 ,  RYTTCCTG_ETS2_B ,  TGANNYRGCA_TCF11MAFG_01 ,  STAT6_02 ,  CTACCTC_LET7A_LET7B_LET7C_LET7D_LET7E_LET7F_MIR98_LET7G_LET7I ,  CTCAAGA_MIR526B ,  ATTCTTT_MIR186 ,  CEBP_Q3 ,  RGAGGAARY_PU1_Q6 ,  STTTCRNTTT_IRF_Q6 ,  TCF11MAFG_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-186

Cytogenetic Map:

3q13.2

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