QuickView for CD316 (gene)

Gene Symbol:: IGSF8 Homo sapiens
Full name:: immunoglobulin superfamily member 8
Synonyms:: CD316, CD81P3, EWI-2, EWI2, KCT-4, LIR-D1, PGRL, immunoglobulin superfamily member 8, CD81 partner 3, glu-Trp-Ile EWI motif-containing protein 2, keratinocytes-associated transmembrane protein 4, prostaglandin regulatory-like protein
Genomic Location:: Chr 1: 158327754-158335032
Description:: This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions includin...
View Full Description

This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.
View Less

Orthologs:: Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Pan troglodytes , Bos taurus
External Links:: Entrez Gene

Transcription Factor Binding Sites:: E12_Q6 , TGANTCA_AP1_C , EFC_Q6 , GCANCTGNY_MYOD_Q6 , RFX1_01 , GGGAGGRR_MAZ_Q6 , AP1_Q6_01 , CAGGTG_E12_Q6 , NF1_Q6 , NF1_Q6_01 , MYOGENIN_Q6

View More

View Less