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QuickView for CD34 (gene)


Gene Symbol:
CD34 Homo sapiens Homo sapiens
Full name:
CD34 molecule
Synonyms:
hematopoietic progenitor cell antigen CD34, CD34 antigen
Genomic Location:
Chr 1: 206126506-206151306
Description:
The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Canis lupus familiaris Gallus gallus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 1
1q32.2


Transcripts Names
NM_001025109
NM_001773



GO Molecular Function

anion binding | sulfate binding | ion binding | carbohydrate binding | protein binding | transcription factor binding

GO Biological Process

renal filtration | extracellular structure organization | cell motility | negative regulation of peptide secretion | regulation of localization | cell-substrate adhesion | negative regulation of cellular response to heat | regulation of immune system process | regulation of nitric oxide biosynthetic process | negative regulation of neuron death | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | glomerulus development | metanephric glomerulus development | negative regulation of protein secretion | positive regulation of protein secretion | tissue homeostasis | blood vessel morphogenesis | regulation of neuron death | metanephric glomerular mesangial cell differentiation | cellular process | localization | extracellular exosome assembly | glomerular filtration | immune system development | positive regulation of macrophage colony-stimulating factor production | negative regulation of secretion | endothelial cell proliferation | negative regulation of establishment of protein localization | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | metanephric nephron development | anatomical structure homeostasis | negative regulation of wound healing | regulation of angiogenesis | regulation of immune response | regulation of cellular process | regulation of metabolic process | negative regulation of cytokine secretion | transdifferentiation | negative regulation of tumor necrosis factor production | epithelium development | cellular component organization | metanephric glomerular mesangium development | urogenital system development | regulation of peptide secretion | regulation of vasculature development | response to stimulus | negative regulation of protein transport | vasculature development | pericyte cell differentiation | regulation of cellular response to heat | response to stress | negative regulation of tumor necrosis factor superfamily cytokine production | multicellular organismal homeostasis | tube morphogenesis | positive regulation of cytokine secretion | cardiovascular system development | negative regulation of transport | regulation of protein transport | blood circulation | negative regulation of metabolic process | hemopoiesis | cellular component assembly | regulation of wound healing | regulation of odontogenesis | negative regulation of nitric oxide biosynthetic process | regulation of peptide transport | kidney development | negative regulation of reactive oxygen species biosynthetic process | cell-cell signaling | extracellular exosome biogenesis | blood vessel development | leukocyte migration | positive regulation of peptide secretion | regulation of cellular response to stress | regulation of neurotransmitter levels | locomotion | positive regulation of glial cell-derived neurotrophic factor secretion | organelle assembly | system development | endothelium development | negative regulation of secretion by cell | regulation of cellular response to hypoxia | multicellular organism development | positive regulation of granulocyte colony-stimulating factor production | cell migration | glomerulus vasculature development | wound healing | regulation of gene expression | stem cell proliferation | kidney epithelium development | positive regulation of secretion | regulation of blood pressure | negative regulation of cytokine production | regulation of blood coagulation | regulation of nitrogen compound metabolic process | paracrine signaling | positive regulation of cell differentiation | cell proliferation | cell differentiation involved in kidney development | angiogenesis | positive regulation of odontogenesis | regulation of tumor necrosis factor production | negative regulation of response to wounding | cell communication | regulation of cellular metabolic process | hematopoietic stem cell proliferation | regulation of macrophage colony-stimulating factor production | metanephros development | cell differentiation involved in metanephros development | negative regulation of interleukin-2 production | homeostatic process | positive regulation of establishment of protein localization | renal system development | vascular wound healing | positive regulation of transport | nephron development | regulation of cytokine secretion | positive regulation of transforming growth factor beta production | regulation of establishment of protein localization | glomerular endothelium development | epithelial cell proliferation | response to wounding | regulation of animal organ morphogenesis | anatomical structure development | regulation of body fluid levels | negative regulation of interleukin-2 secretion | regulation of secretion | cell adhesion | mesangial cell-matrix adhesion | metanephric glomerulus vasculature development | connective tissue development | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | regulation of protein secretion | regulation of vasculogenesis | renal system process | vesicle organization | cell-cell adhesion | positive regulation of cytokine production | angiogenesis involved in wound healing | positive regulation of protein transport | regulation of reactive oxygen species biosynthetic process | anatomical structure formation involved in morphogenesis | positive regulation of vasculogenesis | regulation of response to wounding | positive regulation of interleukin-10 production | signaling | cell-matrix adhesion | regulation of cytokine production | anatomical structure morphogenesis | regulation of developmental process | developmental process | organelle organization | negative regulation of coagulation | tube development | regulation of transport | regulation of reactive oxygen species metabolic process | epithelial cell differentiation | negative regulation of blood coagulation | positive regulation of metabolic process | immune system process | hematopoietic or lymphoid organ development | regulation of protein localization | regulation of cell death | negative regulation of cell death | circulatory system development | glomerular epithelium development | positive regulation of angiogenesis | extracellular vesicle biogenesis | negative regulation of reactive oxygen species metabolic process | negative regulation of cellular response to hypoxia | signal transduction | positive regulation of gene expression | multicellular organismal process

GO Cellular Component

integral component of membrane | basal plasma membrane | intracellular membrane-bounded organelle | apical plasma membrane | basal part of cell | cell | intercellular bridge | intrinsic component of membrane | external side of plasma membrane | cytoplasm | intracellular organelle | apical part of cell | protein-containing complex | plasma membrane | vacuole | perinuclear region of cytoplasm | lytic vacuole | integral component of plasma membrane | extracellular region | membrane-bounded organelle | organelle | glomerular endothelium fenestra | lysosome | cell periphery | pore complex | basolateral plasma membrane | cell surface | intracellular | membrane | intrinsic component of plasma membrane