QuickView for CD6 (gene)

Gene Symbol:

CD6 Homo sapiens

Full name:

CD6 molecule

Synonyms:

TP120, T-cell differentiation antigen CD6, CD6 antigen, T12

Genomic Location:

Chr 11: 60495750-60544425

Description:

This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be as...

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This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RYTTCCTG_ETS2_B ,  AML_Q6 ,  AML1_01 ,  RACCACAR_AML_Q6 ,  PTF1BETA_Q6 ,  AML1_Q6 ,  COREBINDINGFACTOR_Q6

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-216

Cytogenetic Map:

11q12.2

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