QuickView for CD85 (gene)

Gene Symbol:

LILRA5 Homo sapiens

Full name:

leukocyte immunoglobulin like receptor A5

Synonyms:

CD85, CD85F, ILT-11, ILT11, LILRB7, LIR-9, LIR9, leukocyte immunoglobulin-like receptor subfamily A member 5, CD85 antigen-like family member F, immunoglobulin-like transcript 11 protein, leucocyte Ig-like receptor A5, leukocyte Ig-like receptor 9, leukocyte immunoglobulin-like receptor 9, leukocyte immunoglobulin-like receptor subfamily A member 5 soluble, leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 7

Genomic Location:

Chr 19: 59510165-59516221

Description:

The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which...

View Full Description

The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Bos taurus

External Links:

Entrez Gene

Cytogenetic Map:

19q13.42

search → result