QuickView for CDC42EP3;jsessionid=30245802A714087DFE308A48D613EDCE (gene)

Gene Symbol:

CDC42EP3 Homo sapiens

Full name:

CDC42 effector protein 3

Synonyms:

BORG2, CEP3, UB1, cdc42 effector protein 3, CDC42 effector protein (Rho GTPase binding) 3, CRIB-containing BORG2 protein, MSE55-related Cdc42-binding protein, MSE55-related protein, binder of Rho GTPases 2

Genomic Location:

Chr 2: 37724247-37752830

Description:

This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia ...

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This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NKX25_01 ,  TGGAAA_NFAT_Q4_01 ,  FREAC7_01 ,  HNF3ALPHA_Q6 ,  TTTGCAG_MIR518A2 ,  OCT1_04 ,  RSRFC4_01 ,  HFH3_01 ,  OCT1_01 ,  HEN1_01 ,  GATA_Q6 ,  YTATTTTNR_MEF2_02 ,  GCANCTGNY_MYOD_Q6 ,  AAANWWTGC_UNKNOWN ,  GAGACTG_MIR452 ,  RSRFC4_Q2 ,  IPF1_Q4 ,  LYF1_01 ,  AMEF2_Q6 ,  GATAAGR_GATA_C ,  CTTTGA_LEF1_Q2 ,  TTF1_Q6 ,  CTAWWWATA_RSRFC4_Q2 ,  GATA1_04 ,  TGACCTY_ERR1_Q2 ,  WTGAAAT_UNKNOWN ,  GGGAGGRR_MAZ_Q6 ,  TATAAA_TATA_01 ,  CEBPB_01 ,  MEF2_01 ,  CAGGTG_E12_Q6 ,  TST1_01 ,  NKX62_Q2 ,  GCAAAAA_MIR129 ,  HNF3B_01 ,  GGGCGGR_SP1_Q6 ,  YKACATTT_UNKNOWN ,  GATA6_01 ,  TGCCAAR_NF1_Q6 ,  POU1F1_Q6 ,  GATA1_02 ,  OCT1_06 ,  HMEF2_Q6 ,  AR_Q2 ,  HAND1E47_01 ,  TAATTA_CHX10_01 ,  AFP1_Q6 ,  MEF2_03 ,  HEN1_02 ,  TEF_Q6 ,  CP2_02 ,  RYAAAKNNNNNNTTGW_UNKNOWN ,  TGACAGNY_MEIS1_01 ,  CTTTGT_LEF1_Q2 ,  TBP_01 ,  CAGCTG_AP4_Q5 ,  MMEF2_Q6 ,  CDC5_01 ,  SRY_02 ,  TGACATY_UNKNOWN ,  TCF1P_Q6 ,  CEBPGAMMA_Q6 ,  GGGTGGRR_PAX4_03 ,  MEF2_Q6_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-129 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-450 ,  Predicted Gene Targets for miR-410

Cytogenetic Map:

2p22.2

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