QuickView for CDC42EP4;jsessionid=30245802A714087DFE308A48D613EDCE (gene)

Gene Symbol:

CDC42EP4 Homo sapiens

Full name:

CDC42 effector protein 4

Synonyms:

BORG4, CEP4, KAIA1777, cdc42 effector protein 4, CDC42 effector protein (Rho GTPase binding) 4, binder of Rho GTPases 4

Genomic Location:

Chr 17: 68791358-68819738

Description:

The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseud...

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The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

PR_Q2 ,  TAL1ALPHAE47_01 ,  WGTTNNNNNAAA_UNKNOWN ,  SREBP1_Q6 ,  GR_Q6_01 ,  GGGAGGRR_MAZ_Q6 ,  TGAYRTCA_ATF3_Q6 ,  TAL1BETAE47_01 ,  GGGCGGR_SP1_Q6 ,  RAAGNYNNCTTY_UNKNOWN ,  WTTGKCTG_UNKNOWN ,  TAL1BETAITF2_01 ,  CTTTGT_LEF1_Q2 ,  TGACATY_UNKNOWN ,  CREB_Q2_01

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Cytogenetic Map:

17q25.1

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