QuickView for CDH4;jsessionid=23CFF1BBEEAD173429C19B48DBA0ACB8 (gene)

Gene Symbol:

CDH4 Homo sapiens

Full name:

cadherin 4

Synonyms:

CAD4, R-CAD, RCAD, cadherin-4, R-cadherin, cadherin 4, type 1, R-cadherin (retinal), cadherin 4, type 1, preproprotein, retinal cadherin

Genomic Location:

Chr 20: 59260952-59945694

Description:

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during...

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This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Bos taurus ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AAGCACT_MIR520F

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-26

Cytogenetic Map:

20q13.33

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