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QuickView for CELF4;jsessionid=75E8B6B43AC546F4806844DE870311A5 (gene)


Gene Symbol:
CELF4 Homo sapiens Homo sapiens
Full name:
CUGBP Elav-like family member 4
Synonyms:
BRUNOL4, CELF-4, CUGBP Elav-like family member 4, CUG-BP- and ETR-3-like factor 4, LYST-interacting protein LIP9, RNA-binding protein BRUNOL4, bruno-like 4, RNA binding protein, bruno-like protein 4
Genomic Location:
Chr 18: 33077828-33399941
Description:
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple tra...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Danio rerio Pan troglodytes Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
TGGAAA_NFAT_Q4_01 E12_Q6 FREAC7_01 HNF3ALPHA_Q6 RSRFC4_01 HFH3_01 ZF5_01 GCANCTGNY_MYOD_Q6 FOXD3_01 GGGACCA_MIR133A_MIR133B
Cytogenetic Map:
chr 18
18q12.2





GO Molecular Function

nucleic acid binding | mRNA binding | translation regulator activity, nucleic acid binding | pre-mRNA binding | translation repressor activity | organic cyclic compound binding | translation regulator activity | translation repressor activity, mRNA regulatory element binding | BRE binding | heterocyclic compound binding | RNA binding

GO Biological Process

RNA metabolic process | negative regulation of excitatory postsynaptic potential | RNA processing | developmental process involved in reproduction | negative regulation of cellular process | cell differentiation | regulation of mRNA processing | cellular process | negative regulation of signaling | multicellular organismal reproductive process | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of neurological system process | gamete generation | regulation of cellular process | regulation of metabolic process | spliceosomal complex assembly | regulation of mRNA splicing, via spliceosome | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | RNA splicing | negative regulation of neurological system process | RNA splicing, via transesterification reactions | germ cell development | posttranscriptional regulation of gene expression | positive regulation of RNA splicing | reproduction | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular component assembly | positive regulation of mRNA processing | mRNA metabolic process | modulation of chemical synaptic transmission | embryo development | alternative mRNA splicing, via spliceosome | translation regulator activity, nucleic acid binding | regulation of membrane potential | regulation of retina development in camera-type eye | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | modulation of excitatory postsynaptic potential | multicellular organism development | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | negative regulation of RNA splicing | regulation of cellular protein metabolic process | cellular protein-containing complex assembly | translation repressor activity | negative regulation of mRNA processing | regulation of alternative mRNA splicing, via spliceosome | mRNA splice site selection | regulation of cellular metabolic process | regulation of protein metabolic process | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | multicellular organism reproduction | positive regulation of mRNA splicing, via spliceosome | protein-containing complex assembly | translation regulator activity | translation repressor activity, mRNA regulatory element binding | anatomical structure development | metabolic process | regulation of RNA splicing | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | negative regulation of cellular protein metabolic process | gene expression | ribonucleoprotein complex assembly | negative regulation of translation | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of signal transduction | cell development | regulation of developmental process | developmental process | heterocycle metabolic process | negative regulation of synaptic transmission | positive regulation of metabolic process | ribonucleoprotein complex biogenesis | cellular metabolic process | mRNA processing | regulation of translation | sexual reproduction | mRNA splicing, via spliceosome | negative regulation of mRNA splicing, via spliceosome | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | protein-containing complex | ribonucleoprotein complex | membrane-bounded organelle | nucleus | organelle | intracellular