QuickView for CES2 (gene)

Gene Symbol:

CES2 Homo sapiens

Full name:

carboxylesterase 2

Synonyms:

CE-2, CES2A1, PCE-2, iCE, cocaine esterase, carboxylesterase 2 (intestine, liver), hCE-2, intestinal carboxylesterase; liver carboxylesterase-2, methylumbelliferyl-acetate deacetylase 2

Genomic Location:

Chr 16: 65525848-65536500

Description:

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in...

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This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

IRF1_Q6 ,  MGGAAGTG_GABP_B ,  ELK1_01 ,  SCGGAAGY_ELK1_02

Cytogenetic Map:

16q22.1

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