QuickView for CHKA (gene)

Gene Symbol:

CHKA Homo sapiens

Full name:

choline kinase alpha

Synonyms:

CHK, CK, CKI, EK, choline kinase alpha, CHETK-alpha, ethanolamine kinase

Genomic Location:

Chr 11: 67576902-67645434

Description:

The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this ...

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The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

MCAATNNNNNGCG_UNKNOWN ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  NRSF_01 ,  TGTATGA_MIR4853P ,  TEF1_Q6 ,  SP1_Q4_01 ,  CAGNWMCNNNGAC_UNKNOWN ,  GGGCGGR_SP1_Q6 ,  GTATGAT_MIR154_MIR487 ,  CTTTAAR_UNKNOWN ,  SP1_Q6 ,  WTTGKCTG_UNKNOWN ,  GTGGGTGK_UNKNOWN ,  ISRE_01 ,  SP1_Q6_01 ,  SP1_Q2_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-485-3p ,  Predicted Gene Targets for miR-544

Cytogenetic Map:

11q13.2

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