QuickView for CHMP5 (gene)

Gene Symbol:

CHMP5 Homo sapiens

Full name:

charged multivesicular body protein 5

Synonyms:

C9orf83, CGI-34, HSPC177, PNAS-2, SNF7DC2, Vps60, charged multivesicular body protein 5, SNF7 domain containing 2, SNF7 domain-containing protein 2, apoptosis-related protein PNAS-2, chromatin-modifying protein 5, hVps60, vacuolar protein sorting-associated protein 60

Genomic Location:

Chr 9: 33255000-33271510

Description:

CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear an...

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CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ATCATGA_MIR433

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-433-3p

Cytogenetic Map:

9p13.3

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