QuickView for CHMP6 (gene)
- Gene Symbol:
- CHMP6
Homo sapiens - Full name:
- charged multivesicular body protein 6
- Synonyms:
- VPS20, charged multivesicular body protein 6, chromatin-modifying protein 6, hVps20, vacuolar protein sorting-associated protein 20
- Genomic Location:
- Chr 17: 76580290-76588528
- Description:
-
This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein family. Proteins in this family are part of the ESCRT-III (endosomal sorting complex required for transport III) which degrades surface receptors, and in biosynthesis of endosomes.
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Danio rerio , Schizosaccharomyces pombe , Gallus gallus , Bos taurus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
17q25.3
GO Molecular Function
protein-containing complex binding | protein N-terminus binding | protein binding
GO Biological Process
negative regulation of signaling receptor activity | negative regulation of phosphorylation | nucleus organization | regulation of localization | macroautophagy | establishment of localization | negative regulation of cellular process | negative regulation of kinase activity | negative regulation of protein phosphorylation | intracellular transport | cellular process | establishment of organelle localization | viral budding via host ESCRT complex | localization | protein transport | negative regulation of signaling | ESCRT III complex assembly | macromolecule localization | endomembrane system organization | cell separation after cytokinesis | establishment of localization in cell | negative regulation of cellular metabolic process | interspecies interaction between organisms | regulation of cellular process | regulation of metabolic process | catabolic process | organelle localization | negative regulation of epidermal growth factor receptor signaling pathway | cellular component organization | establishment of chromosome localization | viral life cycle | regulation of peptidyl-tyrosine phosphorylation | chromosome segregation | endosomal transport | negative regulation of protein kinase activity | vacuolar transport | cellular localization | negative regulation of metabolic process | cellular component assembly | organelle assembly | regulation of protein tyrosine kinase activity | regulation of signal transduction | negative regulation of phosphate metabolic process | regulation of exosomal secretion | negative regulation of catalytic activity | sister chromatid segregation | regulation of catalytic activity | regulation of phosphorylation | organic substance transport | cell cycle | multivesicular body assembly | mitotic metaphase plate congression | regulation of nitrogen compound metabolic process | peptide transport | vesicle-mediated transport | cell division | metaphase plate congression | regulation of cellular protein metabolic process | autophagy | nuclear chromosome segregation | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | viral process | regulation of signaling receptor activity | regulation of epidermal growth factor-activated receptor activity | protein-containing complex assembly | regulation of kinase activity | regulation of exocytosis | viral budding | mitotic cell cycle | nuclear division | metabolic process | virion assembly | amide transport | regulation of vesicle-mediated transport | regulation of secretion | multivesicular body organization | negative regulation of ERBB signaling pathway | regulation of epidermal growth factor receptor signaling pathway | negative regulation of cellular protein metabolic process | regulation of phosphate metabolic process | mitotic nuclear division | establishment of protein localization | vesicle organization | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | regulation of ERBB signaling pathway | negative regulation of peptidyl-tyrosine phosphorylation | protein localization | endosome organization | organelle organization | negative regulation of epidermal growth factor-activated receptor activity | regulation of transport | chromosome organization | cellular metabolic process | negative regulation of protein tyrosine kinase activity | mitotic sister chromatid segregation | regulation of signaling | regulation of phosphorus metabolic process
GO Cellular Component
late endosome | organelle membrane | cytoplasmic vesicle | cell | late endosome membrane | ESCRT III complex | cytoplasm | intracellular organelle | endosome membrane | protein-containing complex | endomembrane system | vesicle | extracellular exosome | endosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cytosol | intracellular vesicle | intracellular | membrane
