QuickView for CHN1 (gene)

Gene Symbol:

CHN1 Homo sapiens

Full name:

chimerin 1

Synonyms:

ARHGAP2, CHN, DURS2, NC, RHOGAP2, N-chimaerin, A-chimaerin, Rho GTPase-activating protein 2, a2-chimaerin, alpha-chimerin, chimaerin 1, chimerin (chimaerin) 1, n-chimerin

Genomic Location:

Chr 2: 175372338-175578361

Description:

This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding diffe...

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This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  SMTTTTGT_UNKNOWN ,  TCANNTGAY_SREBP1_01 ,  YTATTTTNR_MEF2_02 ,  CATTGTYY_SOX9_B1 ,  OSF2_Q6 ,  FREAC3_01 ,  MYB_Q6 ,  HLF_01 ,  TTGTTT_FOXO4_01 ,  TGATTTRY_GFI1_01 ,  SRY_02 ,  AACTTT_UNKNOWN ,  ATGAAGG_MIR205

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-205 ,  Predicted Gene Targets for miR-543

Cytogenetic Map:

2q31.1

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