QuickView for CITED2;jsessionid=71A56389FA703FE693C9A4EEC1FAD010 (gene)

Gene Symbol:

CITED2 Homo sapiens

Full name:

Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2

Synonyms:

ASD8, MRG-1, MRG1, P35SRJ, VSD2, cbp/p300-interacting transactivator 2, MSG-related protein 1, MSG1-related gene 1, melanocyte-specific gene 1-related gene 1

Genomic Location:

Chr 6: 139735089-139737478

Description:

The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  CACTGTG_MIR128A_MIR128B ,  SP1_01 ,  RTAAACA_FREAC2_01 ,  CMYB_01 ,  HNF4ALPHA_Q6 ,  SMTTTTGT_UNKNOWN ,  GTGTTGA_MIR505 ,  STAT4_01 ,  TTANTCA_UNKNOWN ,  TCANNTGAY_SREBP1_01 ,  RYTTCCTG_ETS2_B ,  EFC_Q6 ,  OCT1_01 ,  FOXO4_01 ,  YGTCCTTGR_UNKNOWN ,  MYCMAX_03 ,  CACGTG_MYC_Q2 ,  SRF_Q6 ,  STAT6_02 ,  CTACTGT_MIR199A ,  GCANCTGNY_MYOD_Q6 ,  FOXD3_01 ,  AAANWWTGC_UNKNOWN ,  HFH1_01 ,  CTATGCA_MIR153 ,  TTTGTAG_MIR520D ,  AACTGGA_MIR145 ,  HP1SITEFACTOR_Q6 ,  E2F_Q6_01 ,  FXR_IR1_Q6 ,  ATGTACA_MIR493 ,  PAX8_01 ,  E2A_Q2 ,  CTCNANGTGNY_UNKNOWN ,  RFX1_01 ,  TATAAA_TATA_01 ,  CEBPDELTA_Q6 ,  CACCCBINDINGFACTOR_Q6 ,  ACATTCC_MIR1_MIR206 ,  CATTTCA_MIR203 ,  FOXO3_01 ,  FREAC3_01 ,  CAGGTG_E12_Q6 ,  ETS2_B ,  TST1_01 ,  NF1_Q6 ,  HNF3B_01 ,  GGGCGGR_SP1_Q6 ,  SRF_Q4 ,  OCT1_03 ,  HIF1_Q5 ,  MGGAAGTG_GABP_B ,  NKX25_02 ,  EVI1_06 ,  E47_01 ,  TGCCAAR_NF1_Q6 ,  HFH4_01 ,  NF1_Q6_01 ,  TGTTTGY_HNF3_Q6 ,  E2F_Q4_01 ,  RNGTGGGC_UNKNOWN ,  MYB_Q6 ,  TTGCCAA_MIR182 ,  FREAC2_01 ,  ELK1_01 ,  TAATTA_CHX10_01 ,  AACATTC_MIR4093P ,  TTGTTT_FOXO4_01 ,  AAAYRNCTG_UNKNOWN ,  PIT1_Q6 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  STAT5A_04 ,  GTTATAT_MIR410 ,  IK1_01 ,  CTGCAGY_UNKNOWN ,  AGGGCAG_MIR18A ,  T3R_Q6 ,  SRF_Q5_01 ,  CTTTGT_LEF1_Q2 ,  CAGCTG_AP4_Q5 ,  CDC5_01 ,  GCTNWTTGK_UNKNOWN ,  AP4_Q5 ,  YNGTTNNNATT_UNKNOWN ,  TGACATY_UNKNOWN ,  PAX2_02 ,  E2F_Q3_01 ,  HNF1_Q6 ,  HIF1_Q3 ,  STTTCRNTTT_IRF_Q6 ,  FREAC4_01 ,  FOXO4_02 ,  RACTNNRTTTNC_UNKNOWN ,  LMO2COM_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-132 ,  Predicted Gene Targets for miR-145 ,  Predicted Gene Targets for miR-153 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-328 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-203 ,  Predicted Gene Targets for miR-384 ,  Predicted Gene Targets for miR-410 ,  Predicted Gene Targets for miR-452 ,  Predicted Gene Targets for miR-493-5p ,  Predicted Gene Targets for miR-505 ,  Predicted Gene Targets for miR-378

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Cytogenetic Map:

6q24.1

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