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QuickView for CLC-6 (gene)


Gene Symbol:
CLCN6 Homo sapiens Homo sapiens
Full name:
chloride voltage-gated channel 6
Synonyms:
CLC-6, chloride transport protein 6, chloride channel, voltage-sensitive 6
Genomic Location:
Chr 1: 11788794-11825788
Description:
This gene encodes a member of the voltage-dependent chloride channel protein family. Members of this family can function as either chloride channels or antiporters. This protein is primarily localized to late endosomes and functions as a chloride/proton antiporter. Alternate splicing results in both coding and non-coding variants. Additional altern...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 1
1p36.22





GO Molecular Function

anion transmembrane transporter activity | voltage-gated ion channel activity | passive transmembrane transporter activity | voltage-gated anion channel activity | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | ion gated channel activity | chloride channel activity | carbohydrate derivative binding | inorganic anion transmembrane transporter activity | ATP binding | chloride transmembrane transporter activity | anion binding | adenyl nucleotide binding | antiporter activity | active transmembrane transporter activity | purine nucleotide binding | transporter activity | ion transmembrane transporter activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | anion channel activity | secondary active transmembrane transporter activity | purine ribonucleotide binding | voltage-gated channel activity | adenyl ribonucleotide binding | channel activity | drug binding | ion channel activity | heterocyclic compound binding | voltage-gated chloride channel activity | substrate-specific channel activity | small molecule binding

GO Biological Process

establishment of localization | anion transmembrane transporter activity | voltage-gated ion channel activity | cellular process | localization | cellular homeostasis | passive transmembrane transporter activity | anion transport | voltage-gated anion channel activity | regulation of cellular process | transmembrane transporter activity | cellular component organization | chloride transmembrane transport | response to stimulus | ion gated channel activity | chloride channel activity | chloride transport | inorganic anion transport | regulation of cellular component size | inorganic anion transmembrane transporter activity | chloride transmembrane transporter activity | ion transmembrane transport | antiporter activity | active transmembrane transporter activity | ion transmembrane transporter activity | cell communication | homeostatic process | response to mechanical stimulus | anion transmembrane transport | anion channel activity | secondary active transmembrane transporter activity | transmembrane transport | signaling | voltage-gated channel activity | regulation of cell size | channel activity | ion channel activity | ion transport | voltage-gated chloride channel activity | substrate-specific channel activity | cell volume homeostasis | signal transduction

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endosome membrane | endomembrane system | vacuole | vesicle | lytic vacuole | endosome | membrane-bounded organelle | organelle | lysosome | intracellular vesicle | intracellular | lysosomal membrane | membrane | vacuolar membrane