QuickView for CLCA1 (gene)

Gene Symbol:

CLCA1 Homo sapiens

Full name:

chloride channel accessory 1

Synonyms:

CACC, CACC1, CLCRG1, CaCC-1, GOB5, hCLCA1, hCaCC-1, calcium-activated chloride channel regulator 1, CLCA family member 1, chloride channel regulator, calcium-activated chloride channel family member 1, calcium-activated chloride channel protein 1, calcium-dependent chloride channel-1, chloride channel regulator 1, chloride channel, calcium activated, family member 1

Genomic Location:

Chr 1: 86707114-86738565

Description:

This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a ...

View Full Description

This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RTAAACA_FREAC2_01 ,  GGGTGGRR_PAX4_03

Cytogenetic Map:

1p22.3

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