QuickView for CMKDR1 (gene)

Gene Symbol:

CX3CR1 Homo sapiens

Full name:

C-X3-C motif chemokine receptor 1

Synonyms:

CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28, CX3C chemokine receptor 1, C-X3-C CKR-1, CMK-BRL-1, CMK-BRL1, G-protein coupled receptor 13, beta chemokine receptor-like 1, chemokine (C-C) receptor-like 1, chemokine (C-X3-C motif) receptor 1, chemokine (C-X3-C) receptor 1, fractalkine receptor

Genomic Location:

Chr 3: 39279989-39296531

Description:

Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transc...

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Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RYTTCCTG_ETS2_B ,  OCT1_03

Cytogenetic Map:

3p22.2

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