QuickView for CNGB1 (gene)

Gene Symbol:

CNGB1 Homo sapiens

Full name:

cyclic nucleotide gated channel beta 1

Synonyms:

CNCG2, CNCG3L, CNCG4, CNG4, CNGB1B, GAR1, GARP, GARP2, RCNC2, RCNCb, RCNCbeta, RP45, cyclic nucleotide-gated cation channel beta-1, CNG channel beta-1, CNG-4, cyclic nucleotide-gated cation channel 4, cyclic nucleotide-gated cation channel gamma, cyclic nucleotide-gated cation channel modulatory subunit, glutamic-acid-rich protein

Genomic Location:

Chr 16: 56475206-56562513

Description:

In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are ...

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In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Pan troglodytes ,  Danio rerio ,  Canis lupus familiaris ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GGATTA_PITX2_Q2 ,  MTF1_Q4

Cytogenetic Map:

16q21

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