QuickView for CNIH2;jsessionid=9CAD6E748DF0CE512A18DECAAE86D165 (gene)

Gene Symbol:

CNIH2 Homo sapiens

Full name:

cornichon family AMPA receptor auxiliary protein 2

Synonyms:

CNIH-2, Cnil, protein cornichon homolog 2, cornichon homolog 2

Genomic Location:

Chr 11: 65802272-65808259

Description:

The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA r...

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The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFAT_Q4_01 ,  TGGAAA_NFAT_Q4_01 ,  RTAAACA_FREAC2_01 ,  NFAT_Q6 ,  GCANCTGNY_MYOD_Q6 ,  CIZ_01 ,  STAT6_01 ,  SREBP1_Q6 ,  TTF1_Q6 ,  RYTGCNWTGGNR_UNKNOWN ,  TEF1_Q6 ,  RP58_01 ,  RFX1_02 ,  AP4_Q6 ,  PXR_Q2 ,  GGGCGGR_SP1_Q6 ,  GTTGNYNNRGNAAC_UNKNOWN ,  YCATTAA_UNKNOWN ,  RNGTGGGC_UNKNOWN ,  HMGIY_Q6 ,  SNACANNNYSYAGA_UNKNOWN ,  RTTTNNNYTGGM_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  CAGCTG_AP4_Q5 ,  SMAD_Q6 ,  FOXM1_01 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  GGGNNTTTCC_NFKB_Q6_01 ,  LBP1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-185 ,  Predicted Gene Targets for miR-376c

Cytogenetic Map:

11q13.2

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