QuickView for CORIN;jsessionid=254D02B343E6EF13479E09D99C1759B1 (gene)

Gene Symbol:

CORIN Homo sapiens

Full name:

corin, serine peptidase

Synonyms:

ATC2, CRN, Lrp4, PEE5, TMPRSS10, atrial natriuretic peptide-converting enzyme, heart-specific serine proteinase ATC2, pro-ANP-convertase, pro-ANP-converting enzyme, transmembrane protease serine 10

Genomic Location:

Chr 4: 47290775-47534816

Description:

This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pres...

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This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CACCAGC_MIR138 ,  AAAGACA_MIR511 ,  CCANNAGRKGGC_UNKNOWN

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-138

Cytogenetic Map:

4p12

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