QuickView for CP37 (gene)
- Gene Symbol:
- CYP3A7
Homo sapiens - Full name:
- cytochrome P450 family 3 subfamily A member 7
- Synonyms:
- CP37, CYPIIIA7, P-450(HFL33), P-450111A7, P450-HFLA, cytochrome P450 3A7, aryl hydrocarbon hydroxylase, cytochrome P450, family 3, subfamily A, polypeptide 7, cytochrome P450, subfamily IIIA, polypeptide 7, cytochrome P450-HFLA, flavoprotein-linked monooxygenase, microsomal monooxygenase, xenobiotic monooxygenase
- Genomic Location:
- Chr 7: 99140596-99170757
- Description:
-
This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of rel...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
7q22.1
GO Molecular Function
cofactor binding | cation binding | steroid hydroxylase activity | iron ion binding | catalytic activity | estrogen 16-alpha-hydroxylase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | tetrapyrrole binding | oxygen binding | transition metal ion binding | heme binding | drug binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity | small molecule binding
GO Biological Process
cellular process | xenobiotic metabolic process | steroid hydroxylase activity | organic cyclic compound metabolic process | cellular lipid metabolic process | response to stimulus | lipid hydroxylation | cellular response to xenobiotic stimulus | estrogen 16-alpha-hydroxylase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | lipid metabolic process | response to xenobiotic stimulus | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | lipid modification | metabolic process | oxidation-reduction process | organic substance metabolic process | steroid metabolic process | cellular metabolic process | oxidoreductase activity | aromatase activity
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane
