QuickView for CPA1 (gene)

Gene Symbol:

CPA1 Homo sapiens

Full name:

carboxypeptidase A1

Synonyms:

CPA, carboxypeptidase A1, carboxypeptidase A1 (pancreatic), pancreatic carboxypeptidase A

Genomic Location:

Chr 7: 129807591-129815185

Description:

This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to...

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This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA_Q6 ,  GATA6_01

Cytogenetic Map:

7q32.2

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