QuickView for CPT1A (gene)

Gene Symbol:

CPT1A Homo sapiens

Full name:

carnitine palmitoyltransferase 1A

Synonyms:

CPT1, CPT1-L, L-CPT1, carnitine O-palmitoyltransferase 1, liver isoform, CPT I, CPTI-L, carnitine O-palmitoyltransferase I, liver isoform, carnitine palmitoyltransferase 1A (liver), carnitine palmitoyltransferase I, liver

Genomic Location:

Chr 11: 68278664-68365881

Description:

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. ...

View Full Description

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Canis lupus familiaris ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  USF_Q6 ,  MYCMAX_03 ,  CACGTG_MYC_Q2 ,  MAX_01 ,  ARNT_02 ,  COMP1_01 ,  GGGYGTGNY_UNKNOWN ,  TEF1_Q6 ,  GGGCGGR_SP1_Q6 ,  USF_01 ,  WTTGKCTG_UNKNOWN ,  IRF7_01 ,  USF2_Q6 ,  AACTTT_UNKNOWN ,  USF_02 ,  STTTCRNTTT_IRF_Q6 ,  GGGTGGRR_PAX4_03

View More

View Less

Cytogenetic Map:

11q13.3

search → result