QuickView for CTIF;jsessionid=0B861F27E495372F317497BA1F7BE233 (gene)
- Gene Symbol:
- CTIF
Homo sapiens - Full name:
- cap binding complex dependent translation initiation factor
- Synonyms:
- Gm672, KIAA0427, CBP80/20-dependent translation initiation factor
- Genomic Location:
- Chr 18: 44319425-44643582
- Description:
-
CTIF is a component of the CBP80 (NCBP1; MIM 600469)/CBP20 (NCBP2; MIM 605133) translation initiation complex that binds cotranscriptionally to the cap end of nascent mRNA. The CBP80/CBP20 complex is involved in a simultaneous editing and translation step that recognizes premature termination codons (PTCs) in mRNAs and directs PTC-containing mRNAs ...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Bos taurus , Gallus gallus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
18q21.1
GO Molecular Function
nucleic acid binding | translation regulator activity, nucleic acid binding | organic cyclic compound binding | translation activator activity | protein binding | translation regulator activity | heterocyclic compound binding | RNA binding
GO Biological Process
RNA metabolic process | positive regulation of macromolecule biosynthetic process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | positive regulation of cellular biosynthetic process | cellular process | organic substance catabolic process | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | positive regulation of translation | positive regulation of cellular protein metabolic process | cellular aromatic compound metabolic process | mRNA catabolic process | regulation of translational initiation | positive regulation of protein metabolic process | posttranscriptional regulation of gene expression | cellular nitrogen compound metabolic process | negative regulation of metabolic process | mRNA metabolic process | nuclear-transcribed mRNA catabolic process | nucleobase-containing compound catabolic process | translation regulator activity, nucleic acid binding | nitrogen compound metabolic process | regulation of gene expression | RNA catabolic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of cellular protein metabolic process | regulation of cellular metabolic process | translation activator activity | regulation of protein metabolic process | aromatic compound catabolic process | translation regulator activity | cellular macromolecule catabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of gene expression | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | regulation of translation | positive regulation of gene expression | macromolecule metabolic process
GO Cellular Component
cell | cytoplasm | perinuclear region of cytoplasm | cytosol | intracellular
