QuickView for CTNNA1;jsessionid=083FC8BC72B92DC2C29D2CCA3F337934 (gene)

Gene Symbol:

CTNNA1 Homo sapiens

Full name:

catenin alpha 1

Synonyms:

CAP102, MDPT2, catenin alpha-1, alpha-E-catenin, catenin (cadherin-associated protein), alpha 1, 102kDa, renal carcinoma antigen NY-REN-13

Genomic Location:

Chr 5: 138117006-138298622

Description:

This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal ...

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This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

YTATTTTNR_MEF2_02 ,  CAGTGTT_MIR141_MIR200A ,  BRN2_01

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-141

Cytogenetic Map:

5q31.2

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