Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for CTNNBIP1;jsessionid=5063B7D5285FC3E7A9E287E6F4F2366C (gene)


Gene Symbol:
CTNNBIP1 Homo sapiens Homo sapiens
Full name:
catenin beta interacting protein 1
Synonyms:
ICAT, beta-catenin-interacting protein 1, beta-catenin-interacting protein ICAT, inhibitor of beta-catenin and Tcf-4
Genomic Location:
Chr 1: 9830921-9892903
Description:
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Canis lupus familiaris Bos taurus Pan troglodytes Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 1
1p36.22





GO Molecular Function

beta-catenin binding | protein domain specific binding | armadillo repeat domain binding | protein binding

GO Biological Process

regulation of vascular permeability involved in acute inflammatory response | regulation of monocyte differentiation | morphogenesis of an epithelium | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | negative regulation of RNA biosynthetic process | defense response | pattern specification process | regulation of transcription initiation from RNA polymerase II promoter | cellular process | epithelial tube morphogenesis | negative regulation of signaling | negative regulation of nucleic acid-templated transcription | negative regulation of mesenchymal cell proliferation | renal tubule morphogenesis | branching involved in ureteric bud morphogenesis | regulation of myeloid cell differentiation | negative regulation of cellular metabolic process | tissue development | regulation of binding | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | regulation of cellular process | regulation of osteoblast differentiation | regulation of metabolic process | regulation of protein complex assembly | epithelium development | urogenital system development | nephron tubule morphogenesis | response to stimulus | positive regulation of immune system process | response to stress | regulation of cell proliferation | tube morphogenesis | negative regulation of DNA-templated transcription, initiation | regulation of DNA binding | blood circulation | negative regulation of metabolic process | kidney development | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | anterior/posterior pattern specification | regulation of nucleic acid-templated transcription | system development | regulation of signal transduction | ureteric bud development | Wnt signaling pathway | multicellular organism development | kidney morphogenesis | regulation of ossification | regulation of gene expression | kidney epithelium development | animal organ morphogenesis | negative regulation of smooth muscle cell proliferation | regulation of nitrogen compound metabolic process | regulation of vascular permeability | negative regulation of DNA-binding transcription factor activity | negative regulation of DNA binding | regulation of transcription by RNA polymerase II | positive regulation of monocyte differentiation | negative regulation of binding | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | positive regulation of ossification | mesonephric epithelium development | mesonephros development | cell communication | negative regulation of protein binding | regulation of cellular metabolic process | renal tubule development | inflammatory response | regulation of RNA metabolic process | renal system development | nephron development | positive regulation of osteoblast differentiation | ureteric bud morphogenesis | regionalization | tissue morphogenesis | regulation of hemopoiesis | branching morphogenesis of an epithelial tube | regulation of DNA-binding transcription factor activity | anatomical structure development | cell surface receptor signaling pathway | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of protein complex assembly | negative regulation of biosynthetic process | negative regulation of gene expression | nephron morphogenesis | animal organ development | regulation of Wnt signaling pathway | morphogenesis of a branching epithelium | negative regulation of transcription initiation from RNA polymerase II promoter | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | regulation of protein binding | morphogenesis of a branching structure | anatomical structure morphogenesis | regulation of DNA-templated transcription, initiation | regulation of developmental process | regulation of mesenchymal cell proliferation | developmental process | negative regulation of transcription by RNA polymerase II | tube development | negative regulation of cell proliferation | negative regulation of Wnt signaling pathway | acute inflammatory response | positive regulation of myeloid leukocyte differentiation | regulation of smooth muscle cell proliferation | nephron tubule development | regulation of cellular component organization | signal transduction | regulation of signaling | mesonephric tubule development | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | beta-catenin destruction complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular