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QuickView for CTSV (gene)


Gene Symbol:
CTSV Homo sapiens Homo sapiens
Full name:
cathepsin V
Synonyms:
CATL2, CTSL2, CTSU, cathepsin L2, cathepsin L2, preproprotein, cathepsin U
Genomic Location:
Chr 9: 98834758-98841360
Description:
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alter...
Orthologs:
Macaca mulatta
External Links:
Entrez Gene
Cytogenetic Map:
chr 9
9q22.33


Transcripts Names
NM_001333
NM_001201575



GO Molecular Function

peptide binding | carboxypeptidase activity | protein-containing complex binding | hydrolase activity | cysteine-type peptidase activity | catalytic activity | serine hydrolase activity | exopeptidase activity | amide binding | kininogen binding | cysteine-type endopeptidase activity | protein binding | aminopeptidase activity | histone binding | serine-type endopeptidase activity | serine-type peptidase activity | endopeptidase activity | cysteine-type carboxypeptidase activity | peptidase activity

GO Biological Process

response to extracellular stimulus | molting cycle | response to nutrient levels | epidermis morphogenesis | extracellular structure organization | antigen processing and presentation | developmental process involved in reproduction | proteolysis | morphogenesis of an epithelium | gonad development | response to hormone | negative regulation of cellular process | protein processing | cell differentiation | male gamete generation | maternal placenta development | nervous system development | cellular response to extracellular stimulus | regulation of organelle organization | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | reproductive system development | female pregnancy | multicellular organismal reproductive process | response to odorant | cellular response to starvation | Sertoli cell differentiation | carboxypeptidase activity | negative regulation of keratinocyte proliferation | tissue development | regulation of cell differentiation | gamete generation | regulation of cellular process | catabolic process | epithelium development | cellular component organization | development of primary sexual characteristics | regulation of keratinocyte proliferation | response to stimulus | response to stress | regulation of cell proliferation | response to glucose | response to starvation | regulation of epithelial cell differentiation | programmed cell death | reproduction | cellular protein catabolic process | antigen processing and presentation of exogenous peptide antigen via MHC class II | extracellular matrix organization | regulation of actin cytoskeleton reorganization | cysteine-type peptidase activity | system development | cellular response to nutrient levels | nitrogen compound metabolic process | reproductive process | antigen processing and presentation of peptide antigen via MHC class II | regulation of actin cytoskeleton organization | multicellular organism development | hair follicle morphogenesis | cellular response to stress | response to lipid | protein catabolic process | regulation of epidermis development | exopeptidase activity | regulation of keratinocyte differentiation | response to corticosteroid | protein maturation | epidermis development | skin development | cell communication | response to monosaccharide | cysteine-type endopeptidase activity | decidualization | autophagic cell death | multicellular organism reproduction | maternal process involved in female pregnancy | antigen processing and presentation of exogenous antigen | development of primary male sexual characteristics | aminopeptidase activity | negative regulation of epithelial cell proliferation | protein metabolic process | hair cycle | response to organic substance | tissue morphogenesis | male sex differentiation | cellular macromolecule catabolic process | anatomical structure development | metabolic process | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | male gonad development | hair cycle process | organic substance metabolic process | cell death | animal organ development | nerve development | gene expression | serine-type endopeptidase activity | skin epidermis development | serine-type peptidase activity | response to gonadotropin | protein autoprocessing | organonitrogen compound catabolic process | multicellular organism aging | response to organic cyclic compound | endopeptidase activity | regulation of epithelial cell proliferation | cellular protein metabolic process | anatomical structure morphogenesis | reproductive structure development | regulation of developmental process | developmental process | spermatogenesis | cysteine-type carboxypeptidase activity | negative regulation of cell proliferation | epithelial cell differentiation | antigen processing and presentation of peptide antigen | regulation of actin filament-based process | immune system process | cellular metabolic process | placenta development | peptidase activity | sex differentiation | response to carbohydrate | response to steroid hormone | aging | sexual reproduction | extracellular matrix disassembly | regulation of cellular component organization | regulation of epidermal cell differentiation | regulation of cytoskeleton organization | hair follicle development | response to glucocorticoid | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

secretory granule | intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | cytoplasmic vesicle | cell body | actin-based cell projection | cell | nuclear lumen | neuronal cell body | vacuolar lumen | nucleolus | external side of plasma membrane | cytoplasm | intracellular organelle | apical part of cell | cell projection | secretory vesicle | endomembrane system | plasma membrane | perikaryon | vacuole | vesicle | lytic vacuole | extracellular region | microvillus | membrane-bounded organelle | nucleus | organelle | lysosome | extracellular space | cell periphery | membrane-enclosed lumen | lysosomal lumen | intracellular vesicle | cell surface | intracellular | membrane