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QuickView for CYP1B1 (gene)


Gene Symbol:
CYP1B1 Homo sapiens Homo sapiens
Full name:
cytochrome P450 family 1 subfamily B member 1
Synonyms:
ASGD6, CP1B, CYPIB1, GLC3A, P4501B1, cytochrome P450 1B1, aryl hydrocarbon hydroxylase, cytochrome P450, family 1, subfamily B, polypeptide 1, cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile), flavoprotein-linked monooxygenase, microsomal monooxygenase, xenobiotic monooxygenase
Genomic Location:
Chr 2: 38148250-38156796
Description:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as pol...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 2
2p22.2


Transcripts Names
NM_000104
Protein Names
Q53TK1
Q5TZW8
Q16678
Q9H316
Q93089



GO Molecular Function

cofactor binding | cation binding | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | tetrapyrrole binding | oxygen binding | transition metal ion binding | heme binding | drug binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity | small molecule binding

GO Biological Process

extracellular structure organization | cell motility | intracellular signal transduction | positive regulation of apoptotic process | regulation of localization | regulation of programmed cell death | eye development | nitric oxide biosynthetic process | negative regulation of cellular process | positive regulation of developmental process | response to drug | reactive oxygen species metabolic process | epithelial cell migration | estrogen metabolic process | response to antibiotic | blood vessel morphogenesis | sterol metabolic process | cellular process | organic substance catabolic process | regulation of cell motility | localization | toxin metabolic process | epithelium migration | negative regulation of cell migration | response to inorganic substance | tissue development | intrinsic apoptotic signaling pathway | response to hydrogen peroxide | negative regulation of cell motility | regulation of angiogenesis | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | omega-hydroxylase P450 pathway | xenobiotic metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | cellular lipid metabolic process | endothelial cell-cell adhesion | regulation of vasculature development | response to stimulus | vasculature development | monocarboxylic acid metabolic process | negative regulation of cell adhesion | cellular response to xenobiotic stimulus | response to stress | positive regulation of JAK-STAT cascade | endothelial cell migration | cellular nitrogen compound biosynthetic process | alcohol metabolic process | regulation of cell proliferation | tube morphogenesis | programmed cell death | supramolecular fiber organization | positive regulation of vascular endothelial growth factor production | cardiovascular system development | retinol metabolic process | cellular nitrogen compound metabolic process | cellular response to toxic substance | extracellular matrix organization | cellular response to organic cyclic compound | reactive oxygen species biosynthetic process | regulation of cell adhesion | cellular biosynthetic process | blood vessel development | trabecular meshwork development | regulation of nucleic acid-templated transcription | negative regulation of NF-kappaB transcription factor activity | regulation of neurotransmitter levels | locomotion | organic hydroxy compound metabolic process | apoptotic process | retinoid metabolic process | system development | nitrogen compound metabolic process | regulation of signal transduction | cellular response to antibiotic | multicellular organism development | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | cell migration | monooxygenase activity | lipid metabolic process | cellular response to oxidative stress | regulation of hormone levels | regulation of gene expression | cellular response to stress | nervous system process | retina vasculature morphogenesis in camera-type eye | regulation of nitrogen compound metabolic process | regulation of cell migration | small molecule metabolic process | positive regulation of STAT cascade | negative regulation of DNA-binding transcription factor activity | positive regulation of intracellular signal transduction | regulation of cellular component movement | response to oxidative stress | neurotransmitter metabolic process | biosynthetic process | angiogenesis | regulation of cell adhesion mediated by integrin | response to toxic substance | membrane lipid catabolic process | response to xenobiotic stimulus | sensory organ development | cellular response to drug | cell communication | regulation of cellular metabolic process | cellular lipid catabolic process | positive regulation of signal transduction | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | regulation of locomotion | regulation of RNA metabolic process | apoptotic signaling pathway | long-chain fatty acid metabolic process | retinal metabolic process | intrinsic apoptotic signaling pathway in response to oxidative stress | drug metabolic process | carboxylic acid metabolic process | cellular aldehyde metabolic process | reactive nitrogen species metabolic process | response to organic substance | retina development in camera-type eye | regulation of JAK-STAT cascade | retinal blood vessel morphogenesis | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | anatomical structure development | metabolic process | membrane lipid metabolic process | visual perception | regulation of RNA biosynthetic process | oxidation-reduction process | cellular response to hydrogen peroxide | positive regulation of cell death | cell adhesion | cellular response to reactive oxygen species | lipid catabolic process | organic substance metabolic process | cell death | animal organ development | response to reactive oxygen species | sensory perception of light stimulus | epithelial cell-cell adhesion | negative regulation of cellular component movement | positive regulation of programmed cell death | diterpenoid metabolic process | fatty acid metabolic process | cell-cell adhesion | positive regulation of cytokine production | camera-type eye development | anatomical structure formation involved in morphogenesis | sensory perception | icosanoid metabolic process | steroid metabolic process | neurotransmitter biosynthetic process | regulation of cell communication | negative regulation of molecular function | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | collagen fibril organization | organic acid metabolic process | regulation of cytokine production | hormone metabolic process | anatomical structure morphogenesis | epoxygenase P450 pathway | isoprenoid metabolic process | regulation of developmental process | cell death in response to oxidative stress | developmental process | nitric oxide metabolic process | tube development | regulation of reactive oxygen species metabolic process | negative regulation of cell adhesion mediated by integrin | negative regulation of cell proliferation | regulation of vascular endothelial growth factor production | retina vasculature development in camera-type eye | cellular metabolic process | ameboidal-type cell migration | cellular response to organic substance | regulation of cell death | oxidoreductase activity | aromatase activity | circulatory system development | arachidonic acid metabolic process | negative regulation of locomotion | positive regulation of angiogenesis | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | mitochondrion | membrane-bounded organelle | organelle | intracellular | membrane