QuickView for CYP24A1 (gene)

Gene Symbol:

CYP24A1 Homo sapiens

Full name:

cytochrome P450 family 24 subfamily A member 1

Synonyms:

CP24, CYP24, HCAI, HCINF1, P450-CC24, 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 1,25-@dihydroxyvitamin D3 24-hydroxylase, 24-OHase, cytochrome P450 24A1, cytochrome P450, family 24, subfamily A, polypeptide 1, cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase), cytochrome P450-CC24, exo-mitochondrial protein, vitamin D 24-hydroxylase, vitamin D(3) 24-hydroxylase

Genomic Location:

Chr 20: 52203395-52223931

Description:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form...

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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

DR3_Q4 ,  VDR_Q3 ,  TTGCWCAAY_CEBPB_02 ,  ATF4_Q2 ,  VDR_Q6 ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  ALPHACP1_01 ,  AP1FJ_Q2 ,  GGGCGGR_SP1_Q6 ,  CEBPB_02 ,  NFY_01 ,  NFY_Q6 ,  AP1_Q2 ,  GCTNWTTGK_UNKNOWN

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-30

Cytogenetic Map:

20q13.2

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