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QuickView for CYP2C19 (gene)


Gene Symbol:
CYP2C19 Homo sapiens Homo sapiens
Full name:
cytochrome P450 family 2 subfamily C member 19
Synonyms:
CPCJ, CYP2C, CYPIIC17, CYPIIC19, P450C2C, P450IIC19, cytochrome P450 2C19, (R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, S-mephenytoin 4-hydroxylase, cytochrome P-450 II C, cytochrome P450, family 2, subfamily C, polypeptide 19, cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19, cytochrome P450-11A, cytochrome P450-254C, flavoprotein-linked monooxygenase, mephenytoin 4'-hydroxylase, mephenytoin 4-hydroxylase, microsomal monooxygenase, xenobiotic monooxygenase
Genomic Location:
Chr 10: 96512453-96602661
Description:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the an...
Orthologs:
Mus musculus Rattus norvegicus Canis lupus familiaris
External Links:
Entrez Gene
Cytogenetic Map:
chr 10
10q23.33


Transcripts Names
NM_000769
Protein Names
Q9UCD4
P33261
Q8WZB2
P33259
Q8WZB1



GO Molecular Function

cofactor binding | cation binding | enzyme binding | steroid hydroxylase activity | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | arachidonic acid monooxygenase activity | tetrapyrrole binding | oxygen binding | protein binding | transition metal ion binding | heme binding | drug binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | small molecule binding | arachidonic acid epoxygenase activity

GO Biological Process

response to drug | cellular process | omega-hydroxylase P450 pathway | xenobiotic metabolic process | catabolic process | steroid hydroxylase activity | organic cyclic compound metabolic process | cellular lipid metabolic process | response to stimulus | monocarboxylic acid metabolic process | cellular response to xenobiotic stimulus | drug catabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | lipid metabolic process | small molecule metabolic process | exogenous drug catabolic process | response to xenobiotic stimulus | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | long-chain fatty acid metabolic process | arachidonic acid monooxygenase activity | drug metabolic process | carboxylic acid metabolic process | monoterpenoid metabolic process | metabolic process | oxidation-reduction process | organic substance metabolic process | fatty acid metabolic process | icosanoid metabolic process | steroid metabolic process | organic acid metabolic process | epoxygenase P450 pathway | isoprenoid metabolic process | heterocycle metabolic process | cellular metabolic process | oxidoreductase activity | arachidonic acid metabolic process | arachidonic acid epoxygenase activity

GO Cellular Component

intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane