QuickView for CYP2R1 (gene)

Gene Symbol:

CYP2R1 Homo sapiens

Full name:

cytochrome P450 family 2 subfamily R member 1

Synonyms:

vitamin D 25-hydroxylase, cytochrome P450 2R1, cytochrome P450, family 2, R1, cytochrome P450, family 2, subfamily R, polypeptide 1

Genomic Location:

Chr 11: 14856131-14870327

Description:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin ...

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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RCGCANGCGY_NRF1_Q6

Cytogenetic Map:

11p15.2

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