QuickView for CYP3A43 (gene)
- Gene Symbol:
- CYP3A43
Homo sapiens - Full name:
- cytochrome P450 family 3 subfamily A member 43
- Synonyms:
- cytochrome P450 3A43, cytochrome P450, family 3, subfamily A, polypeptide 43, cytochrome P450, subfamily IIIA, polypeptide 43
- Genomic Location:
- Chr 7: 99263572-99302109
- Description:
-
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein has a low level of testosterone hydroxylase activity, and may play a role in aging mechanisms...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Pan troglodytes
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
7q22.1
| Transcripts Names |
|---|
| NM_022820 |
| NM_057095 |
| NM_057096 |
| NR_103869 |
| XM_024446877 |
| NR_103868 |
| NM_001278921 |
| XM_017012545 |
| XM_017012544 |
GO Molecular Function
cofactor binding | cation binding | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | tetrapyrrole binding | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity
GO Biological Process
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | metabolic process | oxidation-reduction process | oxidoreductase activity | aromatase activity
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane
