QuickView for CYR61 (gene)

Gene Symbol:

CYR61 Homo sapiens

Full name:

cysteine rich angiogenic inducer 61

Synonyms:

CCN1, GIG1, IGFBP10, protein CYR61, CCN family member 1, IBP-10, IGF-binding protein 10, IGFBP-10, cysteine-rich heparin-binding protein 61, cysteine-rich, anigogenic inducer, 61, insulin-like growth factor-binding protein 10

Genomic Location:

Chr 1: 85819048-85821978

Description:

The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation.

The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  RTAAACA_FREAC2_01 ,  HNF3ALPHA_Q6 ,  OCT1_B ,  TTANTCA_UNKNOWN ,  TGGNNNNNNKCCAR_UNKNOWN ,  TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D ,  HFH3_01 ,  OCT1_01 ,  AML_Q6 ,  FOXO4_01 ,  YATGNWAAT_OCT_C ,  OCT_Q6 ,  AAAYWAACM_HFH4_01 ,  FOXD3_01 ,  PEA3_Q6 ,  CEBP_Q2_01 ,  E2F_Q6_01 ,  SRY_01 ,  TAGCTTT_MIR9 ,  OCT1_Q5_01 ,  OCT_C ,  TATAAA_TATA_01 ,  TGCAAAC_MIR452 ,  TTGGAGA_MIR5155P_MIR519E ,  GTGACGY_E4F1_Q6 ,  YYCATTCAWW_UNKNOWN ,  TEF1_Q6 ,  ATF_01 ,  TTCYRGAA_UNKNOWN ,  YY1_01 ,  TATA_C ,  HNF3_Q6 ,  NF1_Q6 ,  HNF3B_01 ,  E4F1_Q6 ,  FOXO1_01 ,  CTTTAAR_UNKNOWN ,  GCM_Q2 ,  TGCCAAR_NF1_Q6 ,  HSF_Q6 ,  TGTTTGY_HNF3_Q6 ,  OCT1_06 ,  CEBP_Q3 ,  POU3F2_02 ,  TTGTTT_FOXO4_01 ,  WGGAATGY_TEF1_Q6 ,  AP2REP_01 ,  IK3_01 ,  RGAGGAARY_PU1_Q6 ,  PAX_Q6 ,  E2F_Q2 ,  CTTTGT_LEF1_Q2 ,  AACTTT_UNKNOWN ,  USF_02 ,  GGARNTKYCCA_UNKNOWN ,  NFKB_Q6 ,  SRF_C ,  OLF1_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-145 ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-452 ,  Predicted Gene Targets for miR-543

miRNA binding sites
(Source: miRecords):

hsa-miR-30a* Targeted Genes

Cytogenetic Map:

1p22.3

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