QuickView for Cas3 (gene)

Gene Symbol:

EFS Homo sapiens

Full name:

embryonal Fyn-associated substrate

Synonyms:

CAS3, CASS3, EFS1, EFS2, HEFS, SIN, embryonal Fyn-associated substrate, Cas scaffolding protein family member 3, signal transduction protein (SH3 containing)

Genomic Location:

Chr 14: 22895451-22904682

Description:

The longest protein isoform encoded by this gene contains an SH3 domain, which is known to be important in intracellular signal transduction. The protein encoded by a similiar gene in mice was shown to bind to SH3 domains of protein-tyrosine kinases. The function of this gene is unknown. Three alternatively spliced variants encoding different isofo...

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The longest protein isoform encoded by this gene contains an SH3 domain, which is known to be important in intracellular signal transduction. The protein encoded by a similiar gene in mice was shown to bind to SH3 domains of protein-tyrosine kinases. The function of this gene is unknown. Three alternatively spliced variants encoding different isoforms have been described for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GGGAGGRR_MAZ_Q6 ,  TGAYRTCA_ATF3_Q6 ,  GGGYGTGNY_UNKNOWN ,  GGATTA_PITX2_Q2 ,  CCCNNGGGAR_OLF1_01 ,  TAL1BETAITF2_01 ,  CAGCTG_AP4_Q5 ,  ZF5_B ,  CRX_Q4

Cytogenetic Map:

14q11.2

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