Correlation Engine 2.0
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QuickView for Cdh5 (gene)

Gene Symbol:
CDH5 Homo sapiens Homo sapiens
Full name:
cadherin 5
7B4, CD144, cadherin-5, 7B4 antigen, VE-cadherin, cadherin 5, type 2 (vascular endothelium), cadherin 5, type 2, VE-cadherin (vascular epithelium), cd144 antigen, endothelial-specific cadherin, vascular endothelial cadherin
Genomic Location:
Chr 16: 64958064-64996190
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a class...
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Bos taurus Danio rerio Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 16

Protein Names

GO Molecular Function

beta-catenin binding | cadherin binding | cation binding | enzyme binding | signaling receptor binding | ion channel binding | cytoskeletal protein binding | identical protein binding | ion binding | cell adhesion molecule binding | protein binding | protein homodimerization activity | protein phosphatase binding | protein dimerization activity | calcium ion binding | phosphatase binding | metal ion binding

GO Biological Process

regulation of cell development | negative regulation of cellular process | positive regulation of developmental process | cell-cell adhesion mediated by cadherin | cellular process | negative regulation of inflammatory response | response to growth factor | regulation of cell differentiation | positive regulation of endothelial cell differentiation | cell junction assembly | regulation of angiogenesis | regulation of cellular process | cellular component organization | response to transforming growth factor beta | regulation of establishment of cell polarity | regulation of vasculature development | response to stimulus | vasculature development | regulation of cell proliferation | regulation of epithelial cell differentiation | cardiovascular system development | cellular component assembly | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules | regulation of establishment or maintenance of cell polarity | blood vessel development | system development | adherens junction organization | multicellular organism development | enzyme linked receptor protein signaling pathway | positive regulation of cell differentiation | cell communication | transmembrane receptor protein serine/threonine kinase signaling pathway | regulation of establishment of endothelial barrier | positive regulation of establishment of endothelial barrier | cellular response to transforming growth factor beta stimulus | response to organic substance | anatomical structure development | cell surface receptor signaling pathway | positive regulation of cell development | cell-cell junction assembly | developmental maturation | cell adhesion | cell-cell adhesion | blood vessel maturation | transforming growth factor beta receptor signaling pathway | signaling | regulation of developmental process | developmental process | positive regulation of epithelial cell differentiation | negative regulation of cell proliferation | regulation of endothelial cell differentiation | cell-cell adhesion via plasma-membrane adhesion molecules | cellular response to organic substance | circulatory system development | regulation of inflammatory response | positive regulation of angiogenesis | signal transduction | cellular response to growth factor stimulus | homophilic cell adhesion via plasma membrane adhesion molecules | multicellular organismal process | cell-cell junction organization

GO Cellular Component

occluding junction | integral component of membrane | extrinsic component of membrane | catenin complex | adherens junction | cell | plasma membrane protein complex | extrinsic component of plasma membrane | intrinsic component of membrane | external side of plasma membrane | cell-cell adherens junction | cell-cell junction | protein-containing complex | plasma membrane | apical junction complex | cell periphery | bicellular tight junction | cell surface | cell junction | membrane