QuickView for ClC-K1 (gene)

Gene Symbol:

CLCNKA Homo sapiens

Full name:

chloride voltage-gated channel Ka

Synonyms:

CLCK1, ClC-K1, hClC-Ka, chloride channel protein ClC-Ka, chloride channel Ka, chloride channel, kidney, A, chloride channel, voltage-sensitive Ka

Genomic Location:

Chr 1: 16221073-16233132

Description:

This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to C...

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This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  HNF4ALPHA_Q6 ,  YGTCCTTGR_UNKNOWN ,  CTTTGA_LEF1_Q2 ,  HNF4_DR1_Q3 ,  LEF1_Q2 ,  CAGGTG_E12_Q6 ,  DR1_Q3 ,  COUP_DR1_Q6 ,  HNF4_01_B

Cytogenetic Map:

1p36.13

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