QuickView for ClC (gene)
- Gene Symbol:
- CLC
Homo sapiens - Full name:
- Charcot-Leyden crystal galectin
- Synonyms:
- GAL10, Gal-10, LGALS10, LGALS10A, LPPL_HUMAN, galectin-10, Charcot-Leyden crystal protein, eosinophil lysophospholipase, lectin, galactoside-binding, soluble, 10, lysolecithin acylhydrolase
- Genomic Location:
- Chr 19: 44913735-44920508
- Description:
-
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding ...
- Orthologs:
- Mus musculus , Macaca mulatta
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
19q13.2
GO Molecular Function
phospholipase activity | cysteine-type endopeptidase activity involved in apoptotic process | carboxylic ester hydrolase activity | hydrolase activity | cysteine-type peptidase activity | catalytic activity | hydrolase activity, acting on ester bonds | identical protein binding | lipase activity | cysteine-type endopeptidase activity | carbohydrate binding | protein binding | lysophospholipase activity | endopeptidase activity | peptidase activity
GO Biological Process
regulation of T cell mediated immunity | proteolysis | regulation of immune system process | cellular process | cysteine-type endopeptidase activity involved in apoptotic process | regulation of immune response | regulation of cellular process | regulation of cell proliferation | programmed cell death | regulation of T cell anergy | cysteine-type peptidase activity | apoptotic process | nitrogen compound metabolic process | multicellular organism development | regulation of T cell activation | regulation of activated T cell proliferation | regulation of lymphocyte activation | regulation of tolerance induction | regulation of T cell cytokine production | T cell apoptotic process | regulation of cytokine production involved in immune response | cysteine-type endopeptidase activity | protein metabolic process | anatomical structure development | metabolic process | regulation of adaptive immune response | regulation of T cell tolerance induction | organic substance metabolic process | cell death | regulation of cell activation | endopeptidase activity | regulation of T cell proliferation | regulation of cytokine production | regulation of developmental process | developmental process | peptidase activity | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
cell | cytoplasm | cytosol | intracellular
