QuickView for Cldn3 (gene)

Gene Symbol:

CLDN3 Homo sapiens

Full name:

claudin 3

Synonyms:

C7orf1, CPE-R2, CPETR2, HRVP1, RVP1, claudin-3, CPE-R 2, CPE-receptor 2, Clostridium perfringens enterotoxin receptor 2, ventral prostate.1 protein homolog, ventral prostate.1-like protein

Genomic Location:

Chr 7: 72821263-72822512

Description:

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing ...

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Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GCANCTGNY_MYOD_Q6 ,  GGGYGTGNY_UNKNOWN ,  GTGACGY_E4F1_Q6 ,  ATF_01 ,  CAGGTG_E12_Q6 ,  GGGCGGR_SP1_Q6 ,  E4F1_Q6 ,  YTAAYNGCT_UNKNOWN ,  RRCCGTTA_UNKNOWN ,  STTTCRNTTT_IRF_Q6

Cytogenetic Map:

7q11.23

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