QuickView for Crb3 (gene)

Gene Symbol:

CRB3 Homo sapiens

Full name:

crumbs 3, cell polarity complex component

Synonyms:

protein crumbs homolog 3, crumbs family member 3

Genomic Location:

Chr 19: 6415260-6418232

Description:

This gene encodes a member of the Crumbs family of proteins. This gene is widely expressed in epithelial tissues where the encoded protein isoforms play various roles such as the control of cytokinesis and ciliogenesis or the formation of tight junctions. Alternative splicing results in multiple transcript variants encoding different isoforms.

This gene encodes a member of the Crumbs family of proteins. This gene is widely expressed in epithelial tissues where the encoded protein isoforms play various roles such as the control of cytokinesis and ciliogenesis or the formation of tight junctions. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GABP_B ,  TGANTCA_AP1_C ,  HNF1_01 ,  TGTGTGA_MIR377 ,  CAGGTG_E12_Q6 ,  GGGCGGR_SP1_Q6 ,  AREB6_01 ,  MGGAAGTG_GABP_B ,  AREB6_03 ,  ELK1_01 ,  SCGGAAGY_ELK1_02 ,  NRF2_01 ,  CAGCCTC_MIR4855P ,  ELK1_02 ,  AACTTT_UNKNOWN ,  HNF1_Q6 ,  CTCCAAG_MIR432

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-377 ,  Predicted Gene Targets for miR-485-5p ,  Predicted Gene Targets for miR-410

Cytogenetic Map:

19p13.3

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