QuickView for Cyp4b1 (gene)
- Gene Symbol:
- CYP4B1
Homo sapiens - Full name:
- cytochrome P450 family 4 subfamily B member 1
- Synonyms:
- CYPIVB1, P-450HP, cytochrome P450 4B1, cytochrome P450, family 4, subfamily B, polypeptide 1, cytochrome P450, subfamily IVB, polypeptide 1, cytochrome P450-HP, microsomal monooxygenase
- Genomic Location:
- Chr 1: 47037257-47057608
- Description:
-
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabol...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Pan troglodytes , Bos taurus , Canis lupus familiaris , Gallus gallus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
1p33
GO Molecular Function
cofactor binding | cation binding | toxic substance binding | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | tetrapyrrole binding | oxygen binding | transition metal ion binding | heme binding | drug binding | fluorene oxygenase activity | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity | small molecule binding
GO Biological Process
response to drug | benzene-containing compound metabolic process | cellular process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | fluorene metabolic process | drug catabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | antibiotic metabolic process | exogenous drug catabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | drug metabolic process | biphenyl metabolic process | metabolic process | oxidation-reduction process | organic substance metabolic process | fluorene oxygenase activity | cellular metabolic process | oxidoreductase activity | aromatase activity
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane
