QuickView for DAGLA (gene)
- Gene Symbol:
- DAGLA
Homo sapiens - Full name:
- diacylglycerol lipase alpha
- Synonyms:
- C11orf11, DAGL(ALPHA), DAGLALPHA, NSDDR, sn1-specific diacylglycerol lipase alpha, DGL-alpha, neural stem cell-derived dendrite regulator
- Genomic Location:
- Chr 11: 61204486-61271049
- Description:
-
This gene encodes a diacylglycerol lipase. The encoded enzyme is involved in the biosynthesis of the endocannabinoid 2-arachidonoyl-glycerol.
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Gallus gallus , Pan troglodytes , Bos taurus , Danio rerio , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
11q12.2
GO Molecular Function
cation binding | carboxylic ester hydrolase activity | hydrolase activity | catalytic activity | acylglycerol lipase activity | hydrolase activity, acting on ester bonds | ion binding | lipase activity | metal ion binding
GO Biological Process
cell differentiation | nervous system development | neurogenesis | endocannabinoid signaling pathway | generation of neurons | cellular process | organic substance catabolic process | cannabinoid signaling pathway | acylglycerol catabolic process | regulation of cellular process | catabolic process | cellular lipid metabolic process | response to stimulus | monocarboxylic acid metabolic process | diacylglycerol catabolic process | G-protein coupled receptor signaling pathway | cellular biosynthetic process | cell-cell signaling | regulation of neurotransmitter levels | system development | multicellular organism development | neuroblast proliferation | lipid metabolic process | stem cell proliferation | synaptic signaling | small molecule metabolic process | neurotransmitter metabolic process | cell proliferation | biosynthetic process | G-protein coupled glutamate receptor signaling pathway | cell communication | cellular lipid catabolic process | glycerolipid metabolic process | long-chain fatty acid metabolic process | neutral lipid catabolic process | carboxylic acid metabolic process | diacylglycerol metabolic process | neutral lipid metabolic process | anatomical structure development | cell surface receptor signaling pathway | metabolic process | lipid catabolic process | organic substance metabolic process | neural precursor cell proliferation | fatty acid metabolic process | retrograde trans-synaptic signaling by endocannabinoid | icosanoid metabolic process | neurotransmitter biosynthetic process | signaling | organic acid metabolic process | glutamate receptor signaling pathway | developmental process | cellular metabolic process | acylglycerol metabolic process | arachidonic acid metabolic process | retrograde trans-synaptic signaling | signal transduction | multicellular organismal process
GO Cellular Component
integral component of membrane | synapse | neuron projection | cell | varicosity | intrinsic component of membrane | synaptic membrane | main axon | cell projection | postsynaptic membrane | postsynapse | plasma membrane | cell periphery | axon | membrane
